node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PC1_0360 | PC1_3388 | PC1_0360 | PC1_3388 | KEGG: eca:ECA0375 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: eca:ECA3568 nucleoside triphosphate pyrophosphohydrolase. | 0.900 |
PC1_0360 | dcd | PC1_0360 | PC1_1290 | KEGG: eca:ECA0375 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.907 |
PC1_0360 | ndk | PC1_0360 | PC1_3018 | KEGG: eca:ECA0375 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.916 |
PC1_0360 | pyrG | PC1_0360 | PC1_3387 | KEGG: eca:ECA0375 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.911 |
PC1_3388 | PC1_0360 | PC1_3388 | PC1_0360 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: eca:ECA3568 nucleoside triphosphate pyrophosphohydrolase. | KEGG: eca:ECA0375 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | 0.900 |
PC1_3388 | dcd | PC1_3388 | PC1_1290 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: eca:ECA3568 nucleoside triphosphate pyrophosphohydrolase. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.917 |
PC1_3388 | guaA | PC1_3388 | PC1_3003 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: eca:ECA3568 nucleoside triphosphate pyrophosphohydrolase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.902 |
PC1_3388 | ndk | PC1_3388 | PC1_3018 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: eca:ECA3568 nucleoside triphosphate pyrophosphohydrolase. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
PC1_3388 | pyrG | PC1_3388 | PC1_3387 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: eca:ECA3568 nucleoside triphosphate pyrophosphohydrolase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.947 |
dcd | PC1_0360 | PC1_1290 | PC1_0360 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | KEGG: eca:ECA0375 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | 0.907 |
dcd | PC1_3388 | PC1_1290 | PC1_3388 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: eca:ECA3568 nucleoside triphosphate pyrophosphohydrolase. | 0.917 |
dcd | ndk | PC1_1290 | PC1_3018 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.927 |
dcd | pyrG | PC1_1290 | PC1_3387 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.926 |
guaA | PC1_3388 | PC1_3003 | PC1_3388 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: eca:ECA3568 nucleoside triphosphate pyrophosphohydrolase. | 0.902 |
guaA | ndk | PC1_3003 | PC1_3018 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.538 |
guaA | pnp | PC1_3003 | PC1_0589 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.678 |
guaA | pyrG | PC1_3003 | PC1_3387 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.954 |
guaA | rplE | PC1_3003 | PC1_3810 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.444 |
guaA | rplM | PC1_3003 | PC1_0292 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.788 |
guaA | rpsB | PC1_3003 | PC1_0941 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; KEGG: eca:ECA1031 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.653 |