node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMG11723.1 | SMG11761.1 | SAMN06275492_101286 | SAMN06275492_101287 | Uncharacterized radical SAM protein YgiQ. | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.828 |
SMG11723.1 | SMG13529.1 | SAMN06275492_101286 | SAMN06275492_1029 | Uncharacterized radical SAM protein YgiQ. | Methyltransferase domain-containing protein. | 0.529 |
SMG11723.1 | SMG34236.1 | SAMN06275492_101286 | SAMN06275492_11949 | Uncharacterized radical SAM protein YgiQ. | polyphosphate:AMP phosphotransferase. | 0.688 |
SMG11723.1 | SMG42948.1 | SAMN06275492_101286 | SAMN06275492_13212 | Uncharacterized radical SAM protein YgiQ. | Tetratricopeptide repeat-containing protein. | 0.569 |
SMG11723.1 | lepA | SAMN06275492_101286 | SAMN06275492_101288 | Uncharacterized radical SAM protein YgiQ. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.680 |
SMG11723.1 | murB | SAMN06275492_101286 | SAMN06275492_101285 | Uncharacterized radical SAM protein YgiQ. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.621 |
SMG11723.1 | purC | SAMN06275492_101286 | SAMN06275492_101289 | Uncharacterized radical SAM protein YgiQ. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.453 |
SMG11723.1 | purH | SAMN06275492_101286 | SAMN06275492_101296 | Uncharacterized radical SAM protein YgiQ. | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.454 |
SMG11723.1 | purQ | SAMN06275492_101286 | SAMN06275492_101291 | Uncharacterized radical SAM protein YgiQ. | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.453 |
SMG11723.1 | purS | SAMN06275492_101286 | SAMN06275492_101290 | Uncharacterized radical SAM protein YgiQ. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.453 |
SMG11761.1 | SMG11723.1 | SAMN06275492_101287 | SAMN06275492_101286 | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Uncharacterized radical SAM protein YgiQ. | 0.828 |
SMG11761.1 | SMG34236.1 | SAMN06275492_101287 | SAMN06275492_11949 | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | polyphosphate:AMP phosphotransferase. | 0.610 |
SMG11761.1 | lepA | SAMN06275492_101287 | SAMN06275492_101288 | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.948 |
SMG11761.1 | murB | SAMN06275492_101287 | SAMN06275492_101285 | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.552 |
SMG11761.1 | purC | SAMN06275492_101287 | SAMN06275492_101289 | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.538 |
SMG11761.1 | purH | SAMN06275492_101287 | SAMN06275492_101296 | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.535 |
SMG11761.1 | purQ | SAMN06275492_101287 | SAMN06275492_101291 | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.523 |
SMG11761.1 | purS | SAMN06275492_101287 | SAMN06275492_101290 | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.523 |
SMG13529.1 | SMG11723.1 | SAMN06275492_1029 | SAMN06275492_101286 | Methyltransferase domain-containing protein. | Uncharacterized radical SAM protein YgiQ. | 0.529 |
SMG34236.1 | SMG11723.1 | SAMN06275492_11949 | SAMN06275492_101286 | polyphosphate:AMP phosphotransferase. | Uncharacterized radical SAM protein YgiQ. | 0.688 |