STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMG13683.1Amidohydrolase. (393 aa)    
Predicted Functional Partners:
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
    
 0.441
SMG13707.1
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
  
  
 0.428
pxpA
UPF0271 protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
 
  0.426
SMG42416.1
Acetaldehyde dehydrogenase /alcohol dehydrogenase AdhE; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
    
 0.417
purQ
Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...]
    
  0.415
SMG12168.1
Aspartate aminotransferase.
    
 0.408
SMG13482.1
Ornithine cyclodeaminase/mu-crystallin family protein.
    
 0.408
SMG30683.1
Aspartate aminotransferase.
    
 0.408
SMG15822.1
Cystathione beta-lyase.
    
  0.406
SMG15328.1
Gamma-glutamyltransferase 2. Threonine peptidase. MEROPS family T03.
    
  0.405
Your Current Organism:
Dethiosulfovibrio salsuginis
NCBI taxonomy Id: 561720
Other names: D. salsuginis, DSM 21565, Dethiosulfovibrio salsuginis Diaz-Cardenas et al. 2010, Dethiosulfovibrio sp. USBA 82, KCTC 5659, strain USBA 82
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