STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMG18593.1N-acetyl sugar amidotransferase. (378 aa)    
Predicted Functional Partners:
SMG16967.1
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
 
 0.874
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.840
SMG16814.1
UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing)/GDP/UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolysing).
 
 
 0.827
SMG18596.1
UDP-N-acetylglucosamine 4,6-dehydratase.
 
     0.812
hisF
Cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
 
 0.805
SMG18588.1
Predicted dehydrogenase.
  
  
 0.796
SMG18521.1
N-acetylneuraminate synthase/N,N'-diacetyllegionaminate synthase.
 
 
   0.773
SMG18585.1
Hypothetical protein.
       0.773
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.770
SMG30118.1
Mannose-6-phosphate isomerase, type 2.
    
  0.744
Your Current Organism:
Dethiosulfovibrio salsuginis
NCBI taxonomy Id: 561720
Other names: D. salsuginis, DSM 21565, Dethiosulfovibrio salsuginis Diaz-Cardenas et al. 2010, Dethiosulfovibrio sp. USBA 82, KCTC 5659, strain USBA 82
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.