STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMG43333.1Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase. (228 aa)    
Predicted Functional Partners:
SMG43373.1
ABC-type lipoprotein export system, ATPase component.
  
 0.995
hypA
Hydrogenase nickel incorporation protein HypA/HybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
 
 0.872
SMG43319.1
Ubiquinone/menaquinone biosynthesis C-methylase UbiE.
 
   
 0.869
SMG47884.1
FKBP-type peptidyl-prolyl cis-trans isomerase 2.
    
 
 0.858
SMG43326.1
Iron complex transport system substrate-binding protein.
 
     0.836
SMG43313.1
Extracellular solute-binding protein.
       0.779
SMG28575.1
Membrane-bound hydrogenase subunit beta.
   
 
 0.769
SMG21009.1
Hydrogenase expression/formation protein HypC.
  
  
 0.743
SMG21019.1
Hydrogenase expression/formation protein HypD.
  
  
 0.733
SMG43249.1
Iron complex transport system substrate-binding protein.
 
     0.727
Your Current Organism:
Dethiosulfovibrio salsuginis
NCBI taxonomy Id: 561720
Other names: D. salsuginis, DSM 21565, Dethiosulfovibrio salsuginis Diaz-Cardenas et al. 2010, Dethiosulfovibrio sp. USBA 82, KCTC 5659, strain USBA 82
Server load: low (14%) [HD]