STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshBThe second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family. (341 aa)    
Predicted Functional Partners:
KJG14487.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.954
gshA
Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
   
 
 0.758
KJG13964.1
Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.755
KJG14078.1
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.733
KJG12380.1
Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.733
ggt
Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.719
pepA
Multifunctional aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 
 0.704
KJG12492.1
Aminopeptidase B; Probably plays an important role in intracellular peptide degradation.
   
 
 0.704
KJG12493.1
Aminopeptidase B; Probably plays an important role in intracellular peptide degradation.
   
 
 0.704
pepN
Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.690
Your Current Organism:
Photobacterium iliopiscarium
NCBI taxonomy Id: 56192
Other names: ATCC 51760, CAIM 909, CIP 104755, DSM 9896, LMG 19543, LMG:19543, P. iliopiscarium, Vibrio iliopiscarius, strain PS1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.