STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KKW93003.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (580 aa)    
Predicted Functional Partners:
KKW93004.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.939
KKW93095.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.865
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.817
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
    
 
 0.817
KKW89578.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.751
KKW93002.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.704
KKW90809.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.601
KKW93005.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.586
KKW93006.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.586
KKW94207.1
Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family.
    
  0.536
Your Current Organism:
Sphingobium chungbukense
NCBI taxonomy Id: 56193
Other names: IMSNU 11152, JCM 11454, KCTC 2955, Pseudomonas sp. DJ77, S. chungbukense, Sphingobium chungbukense (Kim et al. 2000) Pal et al. 2005, Sphingomonas chungbukensis, Sphingomonas chungbukensis Kim et al. 2000, Sphingomonas sp. DJ77, strain DJ77
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.