STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chbGConserved hypothetical protein; Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobi [...] (252 aa)    
Predicted Functional Partners:
chbF
Cryptic phospho-beta-glucosidase, NAD(P)-binding; Function experimentally demonstrated in the studied species; enzyme.
 
 
 0.993
chbR
DNA-binding transcriptional dual regulator; Function experimentally demonstrated in the studied species; regulator.
 
   
 0.954
chbC
N,N'-diacetylchitobiose-specific enzyme IIC component of PTS; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
 
   
 0.939
chbB
N,N'-diacetylchitobiose-specific enzyme IIB component of PTS; Function experimentally demonstrated in the studied species; transporter.
 
   
 0.905
chbA
N,N'-diacetylchitobiose-specific enzyme IIA component of PTS; Function experimentally demonstrated in the studied species; transporter.
 
   
 0.814
celA
Putative 6-phospho-beta-glucosidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glycosyl hydrolase 1 family.
  
 
 0.512
arnT
4-amino-4-deoxy-L-arabinose transferase; Function experimentally demonstrated in the studied species; enzyme.
 
  
 0.472
chbA_2
Putative phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
 0.415
bcsZ
endo-1,4-D-glucanase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the glycosyl hydrolase 8 (cellulase D) family.
  
   
 0.400
Your Current Organism:
Escherichia coli IAI1
NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1
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