STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpmE50S ribosomal subunit protein L31; Binds the 23S rRNA. (70 aa)    
Predicted Functional Partners:
relA
(p)ppGpp synthetase I/GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.999
tufA
Protein chain elongation factor EF-Tu (duplicate of tufB); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
 
 0.999
rplJ
50S ribosomal subunit protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 
 0.999
rplM
50S ribosomal subunit protein L13; Function experimentally demonstrated in the studied species; structure.
  
 
 0.967
rplK
50S ribosomal subunit protein L11; Function experimentally demonstrated in the studied species; structure.
  
 
 0.953
efp
Elongation factor EF-P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.
 
 
 0.950
fusA
Protein chain elongation factor EF-G, GTP-binding; Function experimentally demonstrated in the studied species; factor.
   
 
 0.944
rpmB
50S ribosomal subunit protein L28; Function experimentally demonstrated in the studied species; structure; Belongs to the bacterial ribosomal protein bL28 family.
  
 
 0.934
rpmG
50S ribosomal subunit protein L33; Function experimentally demonstrated in the studied species; structure; Belongs to the bacterial ribosomal protein bL33 family.
  
 
 0.931
rplU
50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
 
 
 0.929
Your Current Organism:
Escherichia coli IAI1
NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1
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