node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aceF | gcvH | ECIAI1_0113 | ECIAI1_3023 | Pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2; Function experimentally demonstrated in the studied species; enzyme. | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.789 |
aceF | gor | ECIAI1_0113 | ECIAI1_3645 | Pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2; Function experimentally demonstrated in the studied species; enzyme. | Glutathione oxidoreductase; Function experimentally demonstrated in the studied species; carrier. | 0.863 |
aceF | lipA | ECIAI1_0113 | ECIAI1_0611 | Pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2; Function experimentally demonstrated in the studied species; enzyme. | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.545 |
aceF | lipB | ECIAI1_0113 | ECIAI1_0613 | Pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2; Function experimentally demonstrated in the studied species; enzyme. | Lipoyl-protein ligase; Function experimentally demonstrated in the studied species; enzyme. | 0.567 |
aceF | lpd | ECIAI1_0113 | ECIAI1_0114 | Pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2; Function experimentally demonstrated in the studied species; enzyme. | Lipoamide dehydrogenase, E3 component is part of three enzyme complexes; Function experimentally demonstrated in the studied species; enzyme. | 0.999 |
aceF | lplA | ECIAI1_0113 | ECIAI1_4609 | Pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2; Function experimentally demonstrated in the studied species; enzyme. | Fragment of conserved hypothetical protein, putative transcriptionnal regulator (partial); Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Belongs to the LplA family. | 0.791 |
aceF | prsA | ECIAI1_0113 | ECIAI1_1228 | Pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2; Function experimentally demonstrated in the studied species; enzyme. | Phosphoribosylpyrophosphate synthase; Function experimentally demonstrated in the studied species; enzyme. | 0.776 |
aceF | sucA | ECIAI1_0113 | ECIAI1_0699 | Pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2; Function experimentally demonstrated in the studied species; enzyme. | 2-oxoglutarate decarboxylase, thiamin-requiring; Function experimentally demonstrated in the studied species; enzyme. | 0.978 |
gcvH | aceF | ECIAI1_3023 | ECIAI1_0113 | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2; Function experimentally demonstrated in the studied species; enzyme. | 0.789 |
gcvH | gor | ECIAI1_3023 | ECIAI1_3645 | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glutathione oxidoreductase; Function experimentally demonstrated in the studied species; carrier. | 0.630 |
gcvH | lipA | ECIAI1_3023 | ECIAI1_0611 | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.929 |
gcvH | lipB | ECIAI1_3023 | ECIAI1_0613 | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoyl-protein ligase; Function experimentally demonstrated in the studied species; enzyme. | 0.907 |
gcvH | lpd | ECIAI1_3023 | ECIAI1_0114 | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoamide dehydrogenase, E3 component is part of three enzyme complexes; Function experimentally demonstrated in the studied species; enzyme. | 0.972 |
gcvH | lplA | ECIAI1_3023 | ECIAI1_4609 | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Fragment of conserved hypothetical protein, putative transcriptionnal regulator (partial); Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Belongs to the LplA family. | 0.980 |
gcvH | prsA | ECIAI1_3023 | ECIAI1_1228 | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Phosphoribosylpyrophosphate synthase; Function experimentally demonstrated in the studied species; enzyme. | 0.792 |
gcvH | sucA | ECIAI1_3023 | ECIAI1_0699 | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 2-oxoglutarate decarboxylase, thiamin-requiring; Function experimentally demonstrated in the studied species; enzyme. | 0.861 |
gcvH | sucB | ECIAI1_3023 | ECIAI1_0700 | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyltranssuccinase; Function experimentally demonstrated in the studied species; enzyme. | 0.836 |
gor | aceF | ECIAI1_3645 | ECIAI1_0113 | Glutathione oxidoreductase; Function experimentally demonstrated in the studied species; carrier. | Pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2; Function experimentally demonstrated in the studied species; enzyme. | 0.863 |
gor | gcvH | ECIAI1_3645 | ECIAI1_3023 | Glutathione oxidoreductase; Function experimentally demonstrated in the studied species; carrier. | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.630 |
gor | lplA | ECIAI1_3645 | ECIAI1_4609 | Glutathione oxidoreductase; Function experimentally demonstrated in the studied species; carrier. | Fragment of conserved hypothetical protein, putative transcriptionnal regulator (partial); Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Belongs to the LplA family. | 0.679 |