STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A6R68_03809Uncharacterized protein. (554 aa)    
Predicted Functional Partners:
A6R68_23116
SH2 domain-containing protein.
    
 
 0.610
A6R68_07825
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
   0.605
A6R68_02663
14_3_3 domain-containing protein.
    
   0.605
A6R68_20339
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
   0.605
A6R68_13386
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
 
 0.583
A6R68_19248
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
   0.563
A6R68_22423
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
   0.555
A6R68_02913
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
   0.543
A6R68_16542
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
   0.543
A6R68_01078
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.523
Your Current Organism:
Neotoma lepida
NCBI taxonomy Id: 56216
Other names: N. lepida, desert woodrat
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