STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A6R68_18981Uncharacterized protein; Belongs to the cytochrome P450 family. (512 aa)    
Predicted Functional Partners:
A6R68_03108
Carrier domain-containing protein.
  
 0.920
A6R68_08830
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 0.912
A6R68_04317
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
  
 
 0.908
A6R68_14628
PALB2_WD40 domain-containing protein.
  
 0.905
A6R68_15962
LRAT domain-containing protein.
   
 
 0.904
A6R68_12874
Uncharacterized protein; Belongs to the aldehyde dehydrogenase family.
   
 
 0.901
A6R68_12610
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
 0.901
A6R68_12896
Uncharacterized protein.
  
0.893
A6R68_03368
Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.
   
 0.888
A6R68_12890
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
0.882
Your Current Organism:
Neotoma lepida
NCBI taxonomy Id: 56216
Other names: N. lepida, desert woodrat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.