STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A6R68_21808Uncharacterized protein. (632 aa)    
Predicted Functional Partners:
IL1B
Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.
    
 0.995
A6R68_07644
Ig-like domain-containing protein.
  
0.988
A6R68_05007
Protein kinase domain-containing protein.
    
 0.988
A6R68_13668
Uncharacterized protein.
   
 0.988
A6R68_14342
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.988
A6R68_21387
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.981
A6R68_13093
Uncharacterized protein.
   
 0.975
A6R68_18834
Interleukin-1; Belongs to the IL-1 family.
   
 0.971
A6R68_07783
Protein kinase domain-containing protein.
    
 0.966
A6R68_04975
Interleukin-1.
    
 0.962
Your Current Organism:
Neotoma lepida
NCBI taxonomy Id: 56216
Other names: N. lepida, desert woodrat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.