STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (330 aa)    
Predicted Functional Partners:
A6R68_00914
ATP-grasp domain-containing protein.
 
 0.999
A6R68_11258
ATP-grasp_2 domain-containing protein.
  
 0.998
A6R68_04022
ATP-grasp_2 domain-containing protein.
  
 0.998
A6R68_03833
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
 0.998
A6R68_19869
Ligase_CoA domain-containing protein.
 
 0.998
A6R68_06200
ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.
  
0.997
A6R68_01252
Transket_pyr domain-containing protein.
 
 0.996
A6R68_18992
Transket_pyr domain-containing protein.
 
 0.996
A6R68_13454
Transket_pyr domain-containing protein.
 
 0.994
A6R68_02345
Succ_DH_flav_C domain-containing protein.
  
 0.992
Your Current Organism:
Neotoma lepida
NCBI taxonomy Id: 56216
Other names: N. lepida, desert woodrat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.