fen protein (Grifola frondosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

fen

Flap endonuclease 1. (470 aa)

Predicted Functional Partners:

pcn1_0

0.981

pcn1_1

0.981

Wrn

0.977

A0H81_03601

0.977

wrn_1

0.977

A0H81_13824

0.968

pol3

0.968

MRE11

0.966

dna2

0.957

cdc1

0.935

Your Current Organism:

Grifola frondosa

NCBI taxonomy Id: 5627
Other names: G. frondosa, maitake

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0H81_03601	A0H81_13824	A0A1C7MI50	A0A1C7LQ88	3'-5' exonuclease domain-containing protein.	Uncharacterized protein.	0.844
A0H81_03601	MRE11	A0A1C7MI50	A0A1C7LNW6	3'-5' exonuclease domain-containing protein.	Double-strand break repair protein MRE11; Belongs to the MRE11/RAD32 family.	0.999
A0H81_03601	Wrn	A0A1C7MI50	A0A1C7LNK3	3'-5' exonuclease domain-containing protein.	Werner syndrome ATP-dependent helicase.	0.826
A0H81_03601	cdc1	A0A1C7MI50	A0A1C7MLI8	3'-5' exonuclease domain-containing protein.	DNA polymerase subunit delta-2.	0.791
A0H81_03601	dna2	A0A1C7MI50	A0A1C7MM73	3'-5' exonuclease domain-containing protein.	DNA replication ATP-dependent helicase/nuclease DNA2.	0.997
A0H81_03601	fen	A0A1C7MI50	A0A1C7LTB4	3'-5' exonuclease domain-containing protein.	Flap endonuclease 1.	0.977
A0H81_03601	pcn1_0	A0A1C7MI50	A0A1C7MAK5	3'-5' exonuclease domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.965
A0H81_03601	pcn1_1	A0A1C7MI50	A0A1C7MAN1	3'-5' exonuclease domain-containing protein.	Proliferating cell nuclear antigen.	0.965
A0H81_03601	pol3	A0A1C7MI50	A0A1C7MAX2	3'-5' exonuclease domain-containing protein.	DNA polymerase.	0.844
A0H81_03601	wrn_1	A0A1C7MI50	A0A1C7MQU5	3'-5' exonuclease domain-containing protein.	Werner syndrome ATP-dependent helicase.	0.826
A0H81_13824	A0H81_03601	A0A1C7LQ88	A0A1C7MI50	Uncharacterized protein.	3'-5' exonuclease domain-containing protein.	0.844
A0H81_13824	MRE11	A0A1C7LQ88	A0A1C7LNW6	Uncharacterized protein.	Double-strand break repair protein MRE11; Belongs to the MRE11/RAD32 family.	0.766
A0H81_13824	Wrn	A0A1C7LQ88	A0A1C7LNK3	Uncharacterized protein.	Werner syndrome ATP-dependent helicase.	0.844
A0H81_13824	cdc1	A0A1C7LQ88	A0A1C7MLI8	Uncharacterized protein.	DNA polymerase subunit delta-2.	0.990
A0H81_13824	dna2	A0A1C7LQ88	A0A1C7MM73	Uncharacterized protein.	DNA replication ATP-dependent helicase/nuclease DNA2.	0.858
A0H81_13824	fen	A0A1C7LQ88	A0A1C7LTB4	Uncharacterized protein.	Flap endonuclease 1.	0.968
A0H81_13824	pcn1_0	A0A1C7LQ88	A0A1C7MAK5	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.973
A0H81_13824	pcn1_1	A0A1C7LQ88	A0A1C7MAN1	Uncharacterized protein.	Proliferating cell nuclear antigen.	0.973
A0H81_13824	wrn_1	A0A1C7LQ88	A0A1C7MQU5	Uncharacterized protein.	Werner syndrome ATP-dependent helicase.	0.844
MRE11	A0H81_03601	A0A1C7LNW6	A0A1C7MI50	Double-strand break repair protein MRE11; Belongs to the MRE11/RAD32 family.	3'-5' exonuclease domain-containing protein.	0.999