node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0H81_03601 | FEN11 | A0A1C7MI50 | A0A1C7LWU9 | 3'-5' exonuclease domain-containing protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.977 |
A0H81_03601 | RHM52 | A0A1C7MI50 | A0A1C7LV21 | 3'-5' exonuclease domain-containing protein. | DNA repair and recombination protein rhm52. | 0.999 |
A0H81_03601 | Wrn | A0A1C7MI50 | A0A1C7LNK3 | 3'-5' exonuclease domain-containing protein. | Werner syndrome ATP-dependent helicase. | 0.826 |
A0H81_03601 | atr | A0A1C7MI50 | A0A1C7M243 | 3'-5' exonuclease domain-containing protein. | Serine/threonine-protein kinase atr; Belongs to the PI3/PI4-kinase family. | 0.999 |
A0H81_03601 | mph1 | A0A1C7MI50 | A0A1C7MV64 | 3'-5' exonuclease domain-containing protein. | ATP-dependent DNA helicase mph1. | 0.999 |
A0H81_03601 | rad50 | A0A1C7MI50 | A0A1C7M525 | 3'-5' exonuclease domain-containing protein. | DNA repair protein RAD50. | 0.996 |
A0H81_03601 | rhp51 | A0A1C7MI50 | A0A1C7MNY5 | 3'-5' exonuclease domain-containing protein. | DNA repair protein rhp51; Belongs to the RecA family. | 0.967 |
A0H81_03601 | ssb2_0 | A0A1C7MI50 | A0A1C7MEW9 | 3'-5' exonuclease domain-containing protein. | Replication factor A protein 2. | 0.968 |
A0H81_03601 | ssb2_1 | A0A1C7MI50 | A0A1C7MFX3 | 3'-5' exonuclease domain-containing protein. | Replication factor A protein 2. | 0.968 |
A0H81_03601 | wrn_1 | A0A1C7MI50 | A0A1C7MQU5 | 3'-5' exonuclease domain-containing protein. | Werner syndrome ATP-dependent helicase. | 0.826 |
FEN11 | A0H81_03601 | A0A1C7LWU9 | A0A1C7MI50 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 3'-5' exonuclease domain-containing protein. | 0.977 |
FEN11 | RHM52 | A0A1C7LWU9 | A0A1C7LV21 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA repair and recombination protein rhm52. | 0.973 |
FEN11 | Wrn | A0A1C7LWU9 | A0A1C7LNK3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Werner syndrome ATP-dependent helicase. | 0.977 |
FEN11 | atr | A0A1C7LWU9 | A0A1C7M243 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Serine/threonine-protein kinase atr; Belongs to the PI3/PI4-kinase family. | 0.818 |
FEN11 | mph1 | A0A1C7LWU9 | A0A1C7MV64 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | ATP-dependent DNA helicase mph1. | 0.880 |
FEN11 | rad50 | A0A1C7LWU9 | A0A1C7M525 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA repair protein RAD50. | 0.964 |
FEN11 | rhp51 | A0A1C7LWU9 | A0A1C7MNY5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA repair protein rhp51; Belongs to the RecA family. | 0.965 |
FEN11 | ssb2_0 | A0A1C7LWU9 | A0A1C7MEW9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Replication factor A protein 2. | 0.821 |
FEN11 | ssb2_1 | A0A1C7LWU9 | A0A1C7MFX3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Replication factor A protein 2. | 0.820 |
FEN11 | wrn_1 | A0A1C7LWU9 | A0A1C7MQU5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Werner syndrome ATP-dependent helicase. | 0.977 |