A0H81_11047 protein (Grifola frondosa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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Cooccurrence

Coexpression

Experiments

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[Homology]

Score

A0H81_11047

Uncharacterized protein. (489 aa)

Predicted Functional Partners:

GPD_0

0.444

GPD_1

0.444

gpd

0.444

GAPC3

0.444

CYB2_2

0.425

CYB2_1

0.425

CYB2_0

0.425

A0H81_10037

0.414

ASPSCR1

0.414

A0H81_11211

0.405

Your Current Organism:

Grifola frondosa

NCBI taxonomy Id: 5627
Other names: G. frondosa, maitake

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0H81_10037	A0H81_11047	A0A1C7M553	A0A1C7M1L4	PUB domain-containing protein.	Uncharacterized protein.	0.414
A0H81_11047	A0H81_10037	A0A1C7M1L4	A0A1C7M553	Uncharacterized protein.	PUB domain-containing protein.	0.414
A0H81_11047	A0H81_11211	A0A1C7M1L4	A0A1C7LY33	Uncharacterized protein.	Putative thymidylate synthase.	0.405
A0H81_11047	ASPSCR1	A0A1C7M1L4	A0A1C7M8C7	Uncharacterized protein.	Tether containing UBX domain for GLUT4.	0.414
A0H81_11047	CYB2_0	A0A1C7M1L4	A0A1C7MP56	Uncharacterized protein.	Cytochrome b2, mitochondrial.	0.425
A0H81_11047	CYB2_1	A0A1C7M1L4	A0A1C7LZJ7	Uncharacterized protein.	Cytochrome b2, mitochondrial.	0.425
A0H81_11047	CYB2_2	A0A1C7M1L4	A0A1C7LXV0	Uncharacterized protein.	Cytochrome b2, mitochondrial.	0.425
A0H81_11047	GAPC3	A0A1C7M1L4	A0A1C7MNW5	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase 3, cytosolic.	0.444
A0H81_11047	GPD_0	A0A1C7M1L4	A0A1C7LMV6	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.444
A0H81_11047	GPD_1	A0A1C7M1L4	A0A1C7M1U1	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.444
A0H81_11047	gpd	A0A1C7M1L4	A0A1C7MCE7	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.444
A0H81_11211	A0H81_11047	A0A1C7LY33	A0A1C7M1L4	Putative thymidylate synthase.	Uncharacterized protein.	0.405
ASPSCR1	A0H81_11047	A0A1C7M8C7	A0A1C7M1L4	Tether containing UBX domain for GLUT4.	Uncharacterized protein.	0.414
CYB2_0	A0H81_11047	A0A1C7MP56	A0A1C7M1L4	Cytochrome b2, mitochondrial.	Uncharacterized protein.	0.425
CYB2_0	CYB2_1	A0A1C7MP56	A0A1C7LZJ7	Cytochrome b2, mitochondrial.	Cytochrome b2, mitochondrial.	0.799
CYB2_0	CYB2_2	A0A1C7MP56	A0A1C7LXV0	Cytochrome b2, mitochondrial.	Cytochrome b2, mitochondrial.	0.804
CYB2_1	A0H81_11047	A0A1C7LZJ7	A0A1C7M1L4	Cytochrome b2, mitochondrial.	Uncharacterized protein.	0.425
CYB2_1	CYB2_0	A0A1C7LZJ7	A0A1C7MP56	Cytochrome b2, mitochondrial.	Cytochrome b2, mitochondrial.	0.799
CYB2_1	CYB2_2	A0A1C7LZJ7	A0A1C7LXV0	Cytochrome b2, mitochondrial.	Cytochrome b2, mitochondrial.	0.765
CYB2_2	A0H81_11047	A0A1C7LXV0	A0A1C7M1L4	Cytochrome b2, mitochondrial.	Uncharacterized protein.	0.425

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Network Stats

number of nodes:

11

number of edges:

20

average node degree:

3.64

avg. local clustering coefficient:

0.781

expected number of edges:

12

PPI enrichment p-value:

0.0158

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006261

DNA-templated DNA replication

3 of 17

1.98

1.43

0.0036

GO:0006259

DNA metabolic process

5 of 159

1.23

0.99

0.0036

GO:0006269

DNA replication, synthesis of RNA primer

2 of 8

2.13

0.96

0.0282

GO:0090304

Nucleic acid metabolic process

6 of 342

0.98

0.77

0.0036

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140097

Catalytic activity, acting on DNA

4 of 82

1.42

1.07

0.0057

GO:0003677

DNA binding

5 of 320

0.93

0.57

0.0284

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1990077

Primosome complex

3 of 10

2.21

2.26

0.00015

GO:0005576

Extracellular region

2 of 30

1.56

0.89

0.0237

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7184

DNA replication protein DnaC/insertion sequence putative ATP-binding protein, and DNA strand exchange activity

3 of 5

2.51

2.3

0.00019

CL:752

DNA damage, and DNA replication

3 of 48

1.53

0.99

0.0133

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

dml03030

DNA replication

2 of 14

1.89

0.86

0.0366

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:1990077

Primosome complex

3 of 20

1.91

1.54

0.0020

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