STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POLX_2Retrovirus-related Pol polyprotein from transposon TNT 1-94. (1011 aa)    
Predicted Functional Partners:
mph1
ATP-dependent DNA helicase mph1.
    
  0.899
HAT2
Histone acetyltransferase type B subunit 2.
    
 0.659
ssb2_0
Replication factor A protein 2.
    
 0.645
ssb2_1
Replication factor A protein 2.
    
  0.587
A0H81_04314
Thermolabile hemolysin.
    
  0.575
A0H81_11638
Uncharacterized protein.
    
  0.568
DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase.
    
  0.568
A0H81_03914
Uncharacterized protein.
    
  0.568
RGR1
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
  0.535
A0H81_05215
Uncharacterized protein.
    
  0.535
Your Current Organism:
Grifola frondosa
NCBI taxonomy Id: 5627
Other names: G. frondosa, maitake
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.