node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Btus_3321 | serS | Btus_3321 | Btus_0496 | Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.790 |
acpP | serS | Btus_1444 | Btus_0496 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.934 |
acpP | thrS | Btus_1444 | Btus_2309 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). | 0.719 |
acpP | topA | Btus_1444 | Btus_1485 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.757 |
cysS | guaA | Btus_0131 | Btus_0263 | TIGRFAM: cysteinyl-tRNA synthetase; KEGG: gtn:GTNG_0085 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; Belongs to the class-I aminoacyl-tRNA synthetase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.626 |
cysS | metG | Btus_0131 | Btus_0051 | TIGRFAM: cysteinyl-tRNA synthetase; KEGG: gtn:GTNG_0085 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; Belongs to the class-I aminoacyl-tRNA synthetase family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.695 |
cysS | pheT | Btus_0131 | Btus_2300 | TIGRFAM: cysteinyl-tRNA synthetase; KEGG: gtn:GTNG_0085 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; Belongs to the class-I aminoacyl-tRNA synthetase family. | KEGG: aac:Aaci_2129 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. | 0.678 |
cysS | serS | Btus_0131 | Btus_0496 | TIGRFAM: cysteinyl-tRNA synthetase; KEGG: gtn:GTNG_0085 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; Belongs to the class-I aminoacyl-tRNA synthetase family. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.802 |
cysS | thrS | Btus_0131 | Btus_2309 | TIGRFAM: cysteinyl-tRNA synthetase; KEGG: gtn:GTNG_0085 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; Belongs to the class-I aminoacyl-tRNA synthetase family. | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). | 0.624 |
cysS | topA | Btus_0131 | Btus_1485 | TIGRFAM: cysteinyl-tRNA synthetase; KEGG: gtn:GTNG_0085 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.413 |
cysS | trpS | Btus_0131 | Btus_0626 | TIGRFAM: cysteinyl-tRNA synthetase; KEGG: gtn:GTNG_0085 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; Belongs to the class-I aminoacyl-tRNA synthetase family. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.421 |
cysS | valS | Btus_0131 | Btus_0661 | TIGRFAM: cysteinyl-tRNA synthetase; KEGG: gtn:GTNG_0085 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; Belongs to the class-I aminoacyl-tRNA synthetase family. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.647 |
guaA | cysS | Btus_0263 | Btus_0131 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | TIGRFAM: cysteinyl-tRNA synthetase; KEGG: gtn:GTNG_0085 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.626 |
guaA | metG | Btus_0263 | Btus_0051 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.853 |
guaA | pheT | Btus_0263 | Btus_2300 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | KEGG: aac:Aaci_2129 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. | 0.932 |
guaA | serS | Btus_0263 | Btus_0496 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.647 |
guaA | thrS | Btus_0263 | Btus_2309 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). | 0.775 |
guaA | topA | Btus_0263 | Btus_1485 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.627 |
guaA | trpS | Btus_0263 | Btus_0626 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.618 |
guaA | valS | Btus_0263 | Btus_0661 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.925 |