STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (699 aa)    
Predicted Functional Partners:
Btus_0954
PFAM: Ppx/GppA phosphatase; metal-dependent phosphohydrolase HD sub domain; KEGG: hmo:HM1_0233 exopolyphosphatase, putative.
 
 0.993
ppa
Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
     
 0.914
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
      0.561
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.528
Btus_2430
KEGG: bbe:BBR47_13840 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family.
     
 0.458
Btus_0956
KEGG: chy:CHY_1273 IclR family transcriptional regulator; PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR.
       0.435
purM
TIGRFAM: phosphoribosylformylglycinamidine cyclo- ligase; KEGG: hmo:HM1_3108 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein.
    
 0.426
Your Current Organism:
Kyrpidia tusciae
NCBI taxonomy Id: 562970
Other names: Bacillus tusciae DSM 2912, K. tusciae DSM 2912, Kyrpidia tusciae DSM 2912, Kyrpidia tusciae NBRC 15312, Kyrpidia tusciae str. DSM 2912, Kyrpidia tusciae strain DSM 2912
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.