STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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[Homology]
Score
Saut_0384Phospholipase D/Transphosphatidylase; COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: dma:DMR_01830 cardiolipin synthetase; PFAM: phospholipase D/Transphosphatidylase; SMART: phospholipase D/Transphosphatidylase; SPTR: Q1I2L0 Cardiolipin synthetase; PFAM: Phospholipase D Active site motif. (471 aa)    
Predicted Functional Partners:
Saut_1528
Phosphatidylglycerophosphatase; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
     
 0.919
Saut_0383
Endonuclease/exonuclease/phosphatase; COGs: COG3021 conserved hypothetical protein; InterPro IPR005135; KEGG: pin:Ping_2456 hypothetical protein; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Q87MF7 UPF0294 protein VP2298; PFAM: Endonuclease/Exonuclease/phosphatase family.
       0.779
Saut_0385
KEGG: nis:NIS_1665 hypothetical protein; SPTR: Q9VYU0 CG32662.
       0.773
Saut_1289
Nitrogen-fixing NifU domain protein; InterPro IPR002871; KEGG: tdn:Suden_0148 hypothetical protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: O67045 NifU-like protein; PFAM: NifU-like N terminal domain.
 
 
 
 0.746
Saut_2085
Nitrogen-fixing NifU domain protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
   
 
 0.714
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
  
    0.709
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.648
Saut_0386
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR019494:IPR013702:IPR013656:IPR 013767:IPR003594:IPR003661:IPR013655:IPR008207:IPR001789:I PR001610:IPR000014:IPR000700:IPR005467; KEGG: gme:Gmet_1707 PAS/PAC sensor hybrid histidine kinase; PFAM: domain of unknown function DUF1745; FIST C domain; PAS fold-4 domain protein; PAS fold domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; Hpt domain protein; response regulator receiver; SMART: response regulator receiver; histidine kinase A domain prot [...]
   
 
 0.644
ispDF
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
     
 0.554
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.537
Your Current Organism:
Sulfurimonas autotrophica
NCBI taxonomy Id: 563040
Other names: S. autotrophica DSM 16294, Sulfurimonas autotrophica DSM 16294, Sulfurimonas autotrophica OK10, Sulfurimonas autotrophica str. DSM 16294, Sulfurimonas autotrophica strain DSM 16294
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