STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Saut_0386COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR019494:IPR013702:IPR013656:IPR 013767:IPR003594:IPR003661:IPR013655:IPR008207:IPR001789:I PR001610:IPR000014:IPR000700:IPR005467; KEGG: gme:Gmet_1707 PAS/PAC sensor hybrid histidine kinase; PFAM: domain of unknown function DUF1745; FIST C domain; PAS fold-4 domain protein; PAS fold domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; Hpt domain protein; response regulator receiver; SMART: response regulator receiver; histidine kinase A domain prot [...] (1033 aa)    
Predicted Functional Partners:
Saut_0068
Signal transduction histidine kinase with CheB and CheR activity; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR004358:IPR000780:IPR013655:IPR000673:IPR 013656:IPR003594:IPR013767:IPR003661:IPR001610:IPR000014:I PR000700:IPR002052:IPR005467; KEGG: nis:NIS_1076 two-component sensor histidine kinase; PFAM: MCP methyltransferase CheR-type; PAS fold-3 domain protein; CheB methylesterase; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: MCP methyltransferase CheR-type; PAC re [...]
 
0.994
Saut_0084
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633:IPR000160:IPR001789; KEGG: wsu:WS0806 hypothetical protein; PFAM: EAL domain protein; GGDEF domain containing protein; response regulator receiver; SMART: EAL domain protein; response regulator receiver; GGDEF domain containing protein; SPTR: A0YU61 Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with Response Regulator Receiver modulation; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; TIG [...]
 
0.990
Saut_0624
Response regulator receiver modulated CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR001789:IPR002545; KEGG: tdn:Suden_1531 response regulator receiver (CheY-like) modulated CheW protein; PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver; SPTR: A3ER87 Chemotaxis signal transduction protein; PFAM: CheW-like domain; Response regulator receiver domain.
 
 
 0.990
Saut_1066
COGs: COG2200 FOG: EAL domain; InterPro IPR001633:IPR000160:IPR001789; KEGG: tdn:Suden_0984 response regulator receiver/GGDEF/EAL domain-containing protein; PFAM: EAL domain protein; GGDEF domain containing protein; response regulator receiver; SMART: EAL domain protein; response regulator receiver; GGDEF domain containing protein; SPTR: A3WK81 Signaling protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
0.990
Saut_1954
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633:IPR000160:IPR001789; KEGG: wsu:WS0108 GGDEF family protein; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: A3WK81 Signaling protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
 0.989
Saut_0791
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG2200 FOG: EAL domain; InterPro IPR013655:IPR001633:IPR000160:IPR013767:IPR 001610:IPR000014:IPR000700:IPR001789; KEGG: tdn:Suden_2101 response regulator receiver/GGDEF/PAS/PAC domain-containing protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; SPTR: A0XXT6 Putative orphan protein; putative EAL domain; TIGRFAM: PAS sensor [...]
 
 
0.988
Saut_1075
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: nis:NIS_0118 two-component response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: P0A4I0 Transcriptional regulatory protein dltR; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.988
Saut_1373
Response regulator receiver modulated CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR001789:IPR002545; KEGG: tdn:Suden_1257 response regulator receiver (CheY-like) modulated CheW protein; PFAM: CheW domain protein; response regulator receiver; SMART: response regulator receiver; CheW domain protein; SPTR: Q56AR1 Response regulator protein; PFAM: CheW-like domain; Response regulator receiver domain.
  
 
 0.988
Saut_1540
Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR008207:IPR001789:IPR003594:IPR 003661:IPR005467; KEGG: tdn:Suden_0617 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: A3WN98 Sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; H [...]
 
 
0.988
Saut_1715
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: nam:NAMH_0128 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: A3I701 Transcriptional activator protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 
 0.987
Your Current Organism:
Sulfurimonas autotrophica
NCBI taxonomy Id: 563040
Other names: S. autotrophica DSM 16294, Sulfurimonas autotrophica DSM 16294, Sulfurimonas autotrophica OK10, Sulfurimonas autotrophica str. DSM 16294, Sulfurimonas autotrophica strain DSM 16294
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