STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (350 aa)    
Predicted Functional Partners:
Saut_0643
Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
 
 
 0.999
Saut_0556
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020459:IPR000873; KEGG: sun:SUN_0967 acetyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q0W3Y0 Acetyl-CoA synthetase (AMP-forming); PFAM: AMP-binding enzyme.
   
 
 0.927
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.927
Saut_1577
ATP-citrate lyase/succinyl-CoA ligase; COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR005810:IPR005811:IPR017440; KEGG: sun:SUN_0542 ATP citrate synthase, subunit 2; PFAM: ATP-citrate lyase/succinyl-CoA ligase; SPTR: A1Y9H8 ATP citrate lyase alpha subunit (Fragment); PFAM: CoA-ligase; Citrate synthase.
   
  
 0.594
Saut_0642
SEC-C motif domain protein; COGs: COG3012 conserved hypothetical protein; InterPro IPR004027; KEGG: tdn:Suden_1160 SecC motif-containing protein; PFAM: SEC-C motif domain protein; SPTR: A0Y040 Putative uncharacterized protein; PFAM: SEC-C motif.
       0.556
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.547
Saut_0534
Enoyl-(acyl-carrier-protein) reductase (NADH); COGs: COG0623 Enoyl-(acyl-carrier-protein); InterPro IPR002347; KEGG: tdn:Suden_1751 enoyl-(acyl carrier protein) reductase; SPTR: O24990 Enoyl-[acyl-carrier-protein] reductase [NADH]; PFAM: short chain dehydrogenase.
  
  
 0.536
Saut_0641
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR001633:IPR000160:IPR013767:IPR013656:IPR 000014:IPR000700:IPR000215; KEGG: sun:SUN_1481 hypothetical protein; PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; SPTR: A2V3S4 Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); TIGRFAM: diguanylate cyclase; PAS [...]
       0.506
Saut_2111
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.482
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
    0.453
Your Current Organism:
Sulfurimonas autotrophica
NCBI taxonomy Id: 563040
Other names: S. autotrophica DSM 16294, Sulfurimonas autotrophica DSM 16294, Sulfurimonas autotrophica OK10, Sulfurimonas autotrophica str. DSM 16294, Sulfurimonas autotrophica strain DSM 16294
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