STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
Saut_0980CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR004358:IPR008207:IPR004105:IPR002545:IPR 003594:IPR005467; KEGG: pfs:PFLU5093 putative chemotaxis two-component system, sensor histidine kinase protein; PFAM: ATP-binding region ATPase domain protein; CheW domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; SMART: CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; SPTR: A3EH49 Chemotaxis protein CheA; PFAM: CheW-like domain; Histidine kinase-, DNA g [...] (694 aa)    
Predicted Functional Partners:
Saut_0068
Signal transduction histidine kinase with CheB and CheR activity; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR004358:IPR000780:IPR013655:IPR000673:IPR 013656:IPR003594:IPR013767:IPR003661:IPR001610:IPR000014:I PR000700:IPR002052:IPR005467; KEGG: nis:NIS_1076 two-component sensor histidine kinase; PFAM: MCP methyltransferase CheR-type; PAS fold-3 domain protein; CheB methylesterase; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: MCP methyltransferase CheR-type; PAC re [...]
 
 0.999
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.999
Saut_0977
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: mei:Msip34_2707 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: A3RUD7 Probable chemotaxis coupling protein (CheW); PFAM: CheW-like domain.
 
 0.999
Saut_0624
Response regulator receiver modulated CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR001789:IPR002545; KEGG: tdn:Suden_1531 response regulator receiver (CheY-like) modulated CheW protein; PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver; SPTR: A3ER87 Chemotaxis signal transduction protein; PFAM: CheW-like domain; Response regulator receiver domain.
 
 0.998
Saut_0626
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: tdn:Suden_1529 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: A1HMP9 CheW protein; PFAM: CheW-like domain.
 
 0.998
Saut_1373
Response regulator receiver modulated CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR001789:IPR002545; KEGG: tdn:Suden_1257 response regulator receiver (CheY-like) modulated CheW protein; PFAM: CheW domain protein; response regulator receiver; SMART: response regulator receiver; CheW domain protein; SPTR: Q56AR1 Response regulator protein; PFAM: CheW-like domain; Response regulator receiver domain.
 
 0.998
Saut_0976
Response regulator receiver modulated CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR001789:IPR002545:IPR008162; KEGG: abu:Abu_0617 chemotaxis signal transduction protein CheV; PFAM: response regulator receiver; SMART: CheW domain protein; SPTR: A2UYV5 Response regulator receiver modulated CheW protein; PFAM: CheW-like domain; Response regulator receiver domain.
 
 0.995
Saut_0978
COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004090:IPR004089:IPR003660; KEGG: glo:Glov_1733 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: A0Y480 Putative methyl-accepting chemotaxis sensory transducer; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain.
 
 0.994
Saut_0982
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789; KEGG: hch:HCH_00454 FOG: CheY-like receiver; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: A3GWF9 Chemotaxis regulator-transmits chemoreceptor signals to flagelllar motor components CheY; PFAM: Response regulator receiver domain.
 
 0.989
Saut_0975
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
  
 0.983
Your Current Organism:
Sulfurimonas autotrophica
NCBI taxonomy Id: 563040
Other names: S. autotrophica DSM 16294, Sulfurimonas autotrophica DSM 16294, Sulfurimonas autotrophica OK10, Sulfurimonas autotrophica str. DSM 16294, Sulfurimonas autotrophica strain DSM 16294
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