STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
Saut_0985Histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR004358:IPR015168:IPR003594:IPR001638:IPR 005467; KEGG: abu:Abu_1637 two-component sensor histidine kinase; PFAM: NMT1/THI5 like domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; extracellular solute-binding protein family 3; SPTR: A0Y806 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A [...] (864 aa)    
Predicted Functional Partners:
Saut_0386
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR019494:IPR013702:IPR013656:IPR 013767:IPR003594:IPR003661:IPR013655:IPR008207:IPR001789:I PR001610:IPR000014:IPR000700:IPR005467; KEGG: gme:Gmet_1707 PAS/PAC sensor hybrid histidine kinase; PFAM: domain of unknown function DUF1745; FIST C domain; PAS fold-4 domain protein; PAS fold domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; Hpt domain protein; response regulator receiver; SMART: response regulator receiver; histidine kinase A domain prot [...]
 
0.854
Saut_1540
Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR008207:IPR001789:IPR003594:IPR 003661:IPR005467; KEGG: tdn:Suden_0617 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: A3WN98 Sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; H [...]
 
 0.816
Saut_0068
Signal transduction histidine kinase with CheB and CheR activity; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR004358:IPR000780:IPR013655:IPR000673:IPR 013656:IPR003594:IPR013767:IPR003661:IPR001610:IPR000014:I PR000700:IPR002052:IPR005467; KEGG: nis:NIS_1076 two-component sensor histidine kinase; PFAM: MCP methyltransferase CheR-type; PAS fold-3 domain protein; CheB methylesterase; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: MCP methyltransferase CheR-type; PAC re [...]
 
 
0.799
Saut_0984
COGs: COG3613 Nucleoside 2-deoxyribosyltransferase; InterPro IPR007710; KEGG: rme:Rmet_0577 nucleoside 2-deoxyribosyltransferase; PFAM: nucleoside 2-deoxyribosyltransferase; SPTR: A3LGW1 Putative uncharacterized protein; PFAM: Nucleoside 2-deoxyribosyltransferase.
       0.773
Saut_0982
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789; KEGG: hch:HCH_00454 FOG: CheY-like receiver; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: A3GWF9 Chemotaxis regulator-transmits chemoreceptor signals to flagelllar motor components CheY; PFAM: Response regulator receiver domain.
 
   0.761
Saut_0976
Response regulator receiver modulated CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR001789:IPR002545:IPR008162; KEGG: abu:Abu_0617 chemotaxis signal transduction protein CheV; PFAM: response regulator receiver; SMART: CheW domain protein; SPTR: A2UYV5 Response regulator receiver modulated CheW protein; PFAM: CheW-like domain; Response regulator receiver domain.
 
 
 0.756
Saut_1677
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR001789:IPR003594:IPR003661:IPR005467; KEGG: sun:SUN_1842 hypothetical protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: A0XYU6 Sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 0.733
Saut_0637
Response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160:IPR001789:IPR013767:IPR001610:IPR 000014:IPR000700; KEGG: glo:Glov_3210 response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain containing protein; response regulator receiver; PAS fold domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; response regulator receiver; PAS domain containing protein; SPTR: A3JA35 Sensory box/GGDEF domain protein; TIGRFAM: diguanylate cyclase; PAS senso [...]
   
 0.730
Saut_1794
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR001789:IPR003594:IPR003661:IPR 005467; KEGG: tdn:Suden_0416 histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SPTR: A3UV02 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Nitrate and nitrite sensing; Response regulator receiver domain; His Kina [...]
 
 0.719
Saut_2160
COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789; KEGG: tdn:Suden_1034 response regulator receiver domain-containing protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: A0Y086 Putative response regulator; PFAM: Response regulator receiver domain.
 
 
 
 0.691
Your Current Organism:
Sulfurimonas autotrophica
NCBI taxonomy Id: 563040
Other names: S. autotrophica DSM 16294, Sulfurimonas autotrophica DSM 16294, Sulfurimonas autotrophica OK10, Sulfurimonas autotrophica str. DSM 16294, Sulfurimonas autotrophica strain DSM 16294
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