STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Coexpression
Experiments
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[Homology]
Score
Saut_1462Metal dependent phosphohydrolase; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR006674:IPR003607; KEGG: abu:Abu_2329 HD_GYP domain-containing response regulator; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: A2UZN2 Response regulator receiver modulated metal dependent phosphohydrolase; PFAM: HD domain. (476 aa)    
Predicted Functional Partners:
Saut_0386
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR019494:IPR013702:IPR013656:IPR 013767:IPR003594:IPR003661:IPR013655:IPR008207:IPR001789:I PR001610:IPR000014:IPR000700:IPR005467; KEGG: gme:Gmet_1707 PAS/PAC sensor hybrid histidine kinase; PFAM: domain of unknown function DUF1745; FIST C domain; PAS fold-4 domain protein; PAS fold domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; Hpt domain protein; response regulator receiver; SMART: response regulator receiver; histidine kinase A domain prot [...]
 
 0.817
Saut_1883
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: tdn:Suden_1895 diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: A1HS81 Response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
    0.797
Saut_1058
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160:IPR001610:IPR000700; KEGG: tdn:Suden_2101 response regulator receiver/GGDEF/PAS/PAC domain-containing protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; SPTR: A0YNV2 Regulatory component of sensory transduction system; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
    0.674
Saut_2025
Putative GAF sensor protein; InterPro IPR003018; KEGG: wsu:WS1630 response regulator; PFAM: GAF domain protein; SMART: GAF domain protein; SPTR: A2DG30 3'5'-cyclic nucleotide phosphodiesterase family protein; PFAM: GAF domain.
   
 0.673
Saut_1464
Diguanylate cyclase with PAS/PAC sensor; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160:IPR013656:IPR013767:IPR013587:IPR 001610:IPR000014:IPR000700; KEGG: nis:NIS_0426 hypothetical protein; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; Nitrate and nitrite sensing domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: A3I8I8 Putative uncharacterized protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain; Nitrate and nitrite sensing; PAS fold; TIG [...]
 
 0.632
Saut_1460
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: tdn:Suden_0738 diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: A2V0P8 Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
    0.621
Saut_1540
Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR008207:IPR001789:IPR003594:IPR 003661:IPR005467; KEGG: tdn:Suden_0617 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: A3WN98 Sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; H [...]
 
 0.612
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
       0.592
Saut_0425
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR001789; KEGG: tdn:Suden_1780 diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; SMART: GGDEF domain containing protein; response regulator receiver; SPTR: A0Y2E6 Response regulator/GGDEF domain protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
  
 0.586
Saut_1463
Sulphate transporter; COGs: COG0659 Sulfate permease and related transporter (MFS superfamily); InterPro IPR002645:IPR011547:IPR005479; KEGG: sun:SUN_1168 sulfate transporter; PFAM: sulphate transporter; Sulfate transporter/antisigma-factor antagonist STAS; SPTR: A0Y669 Sulfate permease family protein; PFAM: Sulfate transporter family; STAS domain.
       0.586
Your Current Organism:
Sulfurimonas autotrophica
NCBI taxonomy Id: 563040
Other names: S. autotrophica DSM 16294, Sulfurimonas autotrophica DSM 16294, Sulfurimonas autotrophica OK10, Sulfurimonas autotrophica str. DSM 16294, Sulfurimonas autotrophica strain DSM 16294
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