STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Saut_1492UDP-glucose 4-epimerase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR013120:IPR002225:IPR013692:IPR003869:IPR 001509; KEGG: swd:Swoo_1660 polysaccharide biosynthesis protein CapD; PFAM: polysaccharide biosynthesis protein CapD; Polysaccharide biosynthesis domain protein; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; NAD-dependent epimerase/dehydratase; PRIAM: UDP-glucose 4-epimerase; SPTR: A1EL37 Putative dTDP-4-dehydrorhamnose reductase; PFAM: Polysaccharide biosynthesis protein; Polysaccharide biosynthesis protein C-terminal. (339 aa)    
Predicted Functional Partners:
Saut_1491
COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: geo:Geob_1459 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: A2RPW5 UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
 
 
 0.995
Saut_0142
UDP-4-keto-6-deoxy-N-acetylglucosamine4-aminotra nsferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653:IPR001597:IPR000277:IPR020026; KEGG: ccv:CCV52592_0561 spore coat polysaccharide biosynthesis protein SpsC; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Q2FTQ4 DegT/DnrJ/EryC1/StrS aminotransferase; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; PFAM: DegT [...]
  
 
 0.958
Saut_1509
COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR013096:IPR005835:IPR001538:IPR001468:IPR 006375; KEGG: tdn:Suden_1734 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Nucleotidyl transferase; Cupin 2 conserved barrel domain protein; mannose-6-phosphate isomerase type II; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Q8U382 Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase [...]
  
  
 0.956
Saut_1489
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: pfl:PFL_5104 glycosyl transferase, group 1 family protein; PFAM: glycosyl transferase group 1; SPTR: A3WUD4 Predicted glycosyltransferase; PFAM: Glycosyl transferases group 1.
 
  
 0.928
Saut_0143
UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR013120:IPR002225:IPR003869:IPR002198:IPR 001509:IPR020025; KEGG: abu:Abu_2243 UDP GlcNAc dehydratase/reductase PseB, putative; PFAM: polysaccharide biosynthesis protein CapD; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; SPTR: A0Y162 Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acet [...]
  
  
 
0.911
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
    
 0.911
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
    
 0.904
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
  
 0.900
Saut_1500
DegT/DnrJ/EryC1/StrS aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: sun:SUN_2144 aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Q2NGX1 Predicted pyridoxal-phosphate-dependent aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.865
Saut_1506
DegT/DnrJ/EryC1/StrS aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: cjd:JJD26997_0710 WbdK; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: A3SNH0 Polysaccharide biosynthesis protein; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.865
Your Current Organism:
Sulfurimonas autotrophica
NCBI taxonomy Id: 563040
Other names: S. autotrophica DSM 16294, Sulfurimonas autotrophica DSM 16294, Sulfurimonas autotrophica OK10, Sulfurimonas autotrophica str. DSM 16294, Sulfurimonas autotrophica strain DSM 16294
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