STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
Saut_1868Phosphate ABC transporter membrane protein 2, PhoT family; COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR000515:IPR005672; KEGG: sun:SUN_2270 phosphate ABC transporter, permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: P58655 Phosphate transport system permease protein pstA; TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstA. (268 aa)    
Predicted Functional Partners:
Saut_1867
Phosphate ABC transporter membrane protein 1, PhoT family; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
0.999
pstB
Phosphate ABC transporter ATP-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
 
 0.999
Saut_1866
Phosphate ABC transporter substrate-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
 
 
 0.998
Saut_1870
KEGG: abu:Abu_0090 phosphate transport system regulatory protein PhoU, putative; SPTR: B9ZDV7 Phosphate uptake regulator, PhoU.
  
  
 0.968
Saut_1871
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003594:IPR003661:IPR005467; KEGG: abu:Abu_0093 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: A6UWZ1 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
     
 0.702
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.549
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterPro IPR002547:IPR005121:IPR005147:IPR004532; KEGG: tdn:Suden_0870 phenylalanyl-tRNA synthetase subunit beta; PFAM: ferredoxin-fold anticodon-binding; t-RNA-binding domain protein; tRNA synthetase B5; SPTR: Q30S83 Phenylalanyl-tRNA synthetase beta chain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; glutamate--cysteine ligase [...]
     
 0.540
hisI
COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; InterPro IPR002496:IPR008179; KEGG: tdn:Suden_1875 phosphoribosyl-AMP cyclohydrolase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; SPTR: Q7MAQ8 Histidine biosynthesis bifunctional protein hisIE; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family.
     
 0.491
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.461
ribB
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
 0.433
Your Current Organism:
Sulfurimonas autotrophica
NCBI taxonomy Id: 563040
Other names: S. autotrophica DSM 16294, Sulfurimonas autotrophica DSM 16294, Sulfurimonas autotrophica OK10, Sulfurimonas autotrophica str. DSM 16294, Sulfurimonas autotrophica strain DSM 16294
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