Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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Saut_1908Protein of unknown function UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509; KEGG: tdn:Suden_1901 formate dehydrogenase H large subunit; PFAM: protein of unknown function UPF0102; SPTR: Q30PA6 UPF0102 protein Suden_1901; PFAM: Uncharacterised protein family UPF0102; Belongs to the UPF0102 family. (109 aa)    
Predicted Functional Partners:
Saut_1907
Putative PAS/PAC sensor protein; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR013655:IPR006674:IPR013767:IPR001610:IPR 003607:IPR000014:IPR000700; KEGG: abu:Abu_0994 response regulator receiver; PFAM: metal-dependent phosphohydrolase HD sub domain; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein; metal-dependent phosphohydrolase HD region; PAS domain containing protein; SPTR: A2UZN2 Response regulator receiver modulated metal dependent phosphohydrolase; TIGRFAM: PAS sensor protein; PFA [...]
  
    0.654
Saut_1909
Molybdopterin oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterPro IPR006656:IPR006963:IPR006657:IPR006655:IPR 003016; KEGG: tdn:Suden_1902 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: A3JB72 Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
       0.572
Saut_2115
Sigma 54 interacting domain protein; COGs: COG0606 ATPase with chaperone activity; InterPro IPR000523:IPR002078:IPR004482; KEGG: tdn:Suden_2033 Mg chelatase-related protein; PFAM: magnesium chelatase ChlI subunit; SPTR: A3IYV6 Mg chelatase-related protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: Magnesium chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein.
 
  
 0.537
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
     0.486
Saut_1912
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: tdn:Suden_1905 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: A0Z7M1 Putative uncharacterized protein; PFAM: Aminotransferase class I and II.
       0.460
Saut_1913
KEGG: tdn:Suden_1906 hypothetical protein.
       0.408
Saut_1914
KEGG: tdn:Suden_1907 hypothetical protein.
       0.408
Saut_1708
SMF family protein; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: abu:Abu_0235 smf protein, DNA processing chain A; PFAM: SMF family protein; SPTR: A3WIH9 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA.
 
  
 0.405
Saut_1921
COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; KEGG: tdn:Suden_1913 6-pyruvoyl tetrahydrobiopterin synthase-like; SPTR: A2W2V8 6-pyruvoyl-tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase.
 
    0.401
Your Current Organism:
Sulfurimonas autotrophica
NCBI taxonomy Id: 563040
Other names: S. autotrophica DSM 16294, Sulfurimonas autotrophica DSM 16294, Sulfurimonas autotrophica OK10, Sulfurimonas autotrophica str. DSM 16294, Sulfurimonas autotrophica strain DSM 16294
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