Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Saut_2002Integrase family protein; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: tdn:Suden_0938 phage integrase; PFAM: integrase family protein; SPTR: Q8R890 Tyrosine recombinase xerC-like; PFAM: Phage integrase family; Belongs to the 'phage' integrase family. (417 aa)    
Predicted Functional Partners:
Saut_2003
Hypothetical protein.
       0.773
Saut_0153
Integrase family protein; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: nam:NAMH_1173 phage integrase; PFAM: integrase family protein; SPTR: A3XEU0 Phage integrase; PFAM: Phage integrase family; Belongs to the 'phage' integrase family.
  
     0.504
Saut_2000
Hypothetical protein.
       0.458
Saut_2001
Hypothetical protein.
       0.458
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.448
Saut_1608
Transformation system protein; COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR002375; KEGG: tdn:Suden_1638 transformation system protein; PFAM: Phosphoribosyl transferase domain.
   
    0.430
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.408
Your Current Organism:
Sulfurimonas autotrophica
NCBI taxonomy Id: 563040
Other names: S. autotrophica DSM 16294, Sulfurimonas autotrophica DSM 16294, Sulfurimonas autotrophica OK10, Sulfurimonas autotrophica str. DSM 16294, Sulfurimonas autotrophica strain DSM 16294
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