STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Saut_2039NADH/Ubiquinone/plastoquinone (complex I); COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR001750; KEGG: sun:SUN_0262 Ni-Fe hydrogenase, membrane subunit HyfF; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Q0W2B8 Hydrogenase, membrane subunit 1-like protein (EchA-like); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains. (470 aa)    
Predicted Functional Partners:
Saut_2038
NADH dehydrogenase (ubiquinone) 30 kDa subunit; COGs: COG3261 Ni Fe-hydrogenase III large subunit; InterPro IPR001268; KEGG: sun:SUN_0263 Ni-Fe hydrogenase, large subunit HycE; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; SPTR: Q8PY03 Formate hydrogenlyase subunit 5; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit.
 
 
 0.999
Saut_2041
COGs: COG0650 Formate hydrogenlyase subunit 4; KEGG: sun:SUN_0260 Ni-Fe hydrogenase, membrane subunit HycD/HyfD; SPTR: Q0W2B6 Hydrogenase, membrane subunit 3-like protein (EchB-like); PFAM: NADH dehydrogenase.
 
 
 0.990
Saut_2037
NADH ubiquinone oxidoreductase 20 kDa subunit; COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006137; KEGG: sun:SUN_0264 Ni-Fe hydrogenase, small subunit HycG; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: Q8THY5 Hydrogenase-3, subunit G (HycG-like protein); PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
 
 
 0.989
Saut_2042
NADH/Ubiquinone/plastoquinone (complex I); COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR003918:IPR003916:IPR001750; KEGG: sun:SUN_0259 Ni-Fe hydrogenase, membrane subunit HycC/HyfB; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Q0W2B5 Hydrogenase, membrane subunit 4-like protein (HycC-like); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains.
 
    0.988
Saut_2043
NADH/Ubiquinone/plastoquinone (complex I); COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR003918:IPR003916:IPR001750; KEGG: sun:SUN_0259 Ni-Fe hydrogenase, membrane subunit HycC/HyfB; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Q0W2B5 Hydrogenase, membrane subunit 4-like protein (HycC-like); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains.
 
    0.973
Saut_2040
Ni-Fe hydrogenase, membrane subunit HyfE; COGs: COG4237 Hydrogenase 4 membrane component (E); KEGG: sun:SUN_0261 Ni-Fe hydrogenase, membrane subunit HyfE; SPTR: Q0W2B7 Hydrogenase, membrane subunit 2-like protein.
 
  
 0.971
Saut_1823
COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR018393:IPR003916:IPR001750:IPR001516:IPR 003945; KEGG: tdn:Suden_1817 NADH dehydrogenase subunit L; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; SPTR: Q9PMA7 NADH-quinone oxidoreductase subunit L; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; TIG [...]
 
 
 0.923
Saut_2036
Diguanylate cyclase with PAS/PAC sensor; COGs: COG2199 FOG: GGDEF domain; InterPro IPR013655:IPR000160:IPR001610:IPR000014:IPR 000700; KEGG: tcx:Tcr_1851 diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: A2UVC1 Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain.
       0.610
Saut_0676
Conserved hypothetical protein; COGs: COG2020 Putative protein-S-isoprenylcysteine methyltransferase; KEGG: sun:SUN_1312 hypothetical protein; SPTR: B5IGC3 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1295).
  
     0.600
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.472
Your Current Organism:
Sulfurimonas autotrophica
NCBI taxonomy Id: 563040
Other names: S. autotrophica DSM 16294, Sulfurimonas autotrophica DSM 16294, Sulfurimonas autotrophica OK10, Sulfurimonas autotrophica str. DSM 16294, Sulfurimonas autotrophica strain DSM 16294
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