STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDL83319.1Cell surface protein SprA. (2407 aa)    
Predicted Functional Partners:
SDL80755.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.992
SDL75363.1
Hypothetical protein.
  
 0.991
SDM60860.1
Hypothetical protein.
  
 
 0.989
SDL55515.1
Protein of unknown function.
  
 
   0.988
SDL84622.1
FKBP-type peptidyl-prolyl cis-trans isomerase.
    
   0.907
SDM38999.1
FKBP-type peptidyl-prolyl cis-trans isomerase FklB.
    
   0.907
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.864
SDM24718.1
AAA ATPase domain-containing protein.
     
 0.857
SDL85879.1
Hypothetical protein.
  
 
 0.811
SDM91375.1
Tetratricopeptide repeat-containing protein.
  
   
 0.809
Your Current Organism:
Siphonobacter aquaeclarae
NCBI taxonomy Id: 563176
Other names: DSM 21668, Flexibacteraceae bacterium P2, NCAIM B 02328, S. aquaeclarae, Siphonobacter aquaeclarae Tancsics et al. 2010, strain P2
Server load: low (14%) [HD]