Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFV45600.1Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family. (575 aa)    
Predicted Functional Partners:
EFV44739.1
Acetolactate synthase, small subunit.
 
 0.985
EFV46051.2
Pyruvate:ferredoxin (flavodoxin) oxidoreductase.
  
 
 0.949
EFV44560.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase.
  
 
 0.949
EFV44797.1
Malate dehydrogenase (oxaloacetate-decarboxylating).
   
 0.923
EFV44182.2
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
   
 0.923
EFV43942.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
   
 0.923
EFV45449.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.912
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.910
EFV44958.1
Pyruvate carboxylase.
     
 0.907
EFV45799.1
2-oxoglutarate ferredoxin oxidoreductase subunit beta.
  
 
 0.905
Your Current Organism:
Bilophila wadsworthia
NCBI taxonomy Id: 563192
Other names: B. wadsworthia 3_1_6, Bilophila wadsworthia 3_1_6, Bilophila wadsworthia str. 3_1_6, Bilophila wadsworthia strain 3_1_6
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