Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (366 aa)    
Predicted Functional Partners:
cmk
Cytidylate kinase; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the cytidylate kinase family. Type 1 subfamily.
 
  
  0.978
EFV43771.1
Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.
 
  
 0.927
EFV43772.1
Formate dehydrogenase family accessory protein FdhD.
 
  
 0.922
EFV44601.1
Molybdenum cofactor synthesis domain-containing protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.918
EFV43822.1
Molybdenum cofactor synthesis domain-containing protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 
 0.913
folE2
GTP cyclohydrolase folE2; Converts GTP to 7,8-dihydroneopterin triphosphate.
     
  0.900
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.900
EFV45281.1
Molybdenum cofactor synthesis domain-containing protein.
 
  
 0.889
EFV42535.1
MazG family protein.
    
 0.813
EFV45113.1
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
  0.805
Your Current Organism:
Bilophila wadsworthia
NCBI taxonomy Id: 563192
Other names: B. wadsworthia 3_1_6, Bilophila wadsworthia 3_1_6, Bilophila wadsworthia str. 3_1_6, Bilophila wadsworthia strain 3_1_6
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