node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFV43761.1 | dnaX | HMPREF0179_02453 | HMPREF0179_05205 | YbaB/EbfC family DNA-binding protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.792 |
EFV43761.1 | recR | HMPREF0179_02453 | HMPREF0179_02452 | YbaB/EbfC family DNA-binding protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Recombination protein recR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.889 |
EFV44560.1 | EFV46051.2 | HMPREF0179_01626 | HMPREF0179_00091 | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.999 |
EFV44560.1 | dnaX | HMPREF0179_01626 | HMPREF0179_05205 | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.433 |
EFV44560.1 | recR | HMPREF0179_01626 | HMPREF0179_02452 | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | Recombination protein recR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.840 |
EFV44560.1 | topA | HMPREF0179_01626 | HMPREF0179_03009 | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.999 |
EFV45325.1 | recR | HMPREF0179_00858 | HMPREF0179_02452 | Hypothetical protein. | Recombination protein recR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.681 |
EFV45325.1 | tmk | HMPREF0179_00858 | HMPREF0179_02510 | Hypothetical protein. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.672 |
EFV46051.2 | EFV44560.1 | HMPREF0179_00091 | HMPREF0179_01626 | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.999 |
EFV46051.2 | dnaX | HMPREF0179_00091 | HMPREF0179_05205 | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.433 |
EFV46051.2 | recR | HMPREF0179_00091 | HMPREF0179_02452 | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | Recombination protein recR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.840 |
EFV46051.2 | topA | HMPREF0179_00091 | HMPREF0179_03009 | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.999 |
dnaX | EFV43761.1 | HMPREF0179_05205 | HMPREF0179_02453 | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | YbaB/EbfC family DNA-binding protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | 0.792 |
dnaX | EFV44560.1 | HMPREF0179_05205 | HMPREF0179_01626 | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.433 |
dnaX | EFV46051.2 | HMPREF0179_05205 | HMPREF0179_00091 | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.433 |
dnaX | recR | HMPREF0179_05205 | HMPREF0179_02452 | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Recombination protein recR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.725 |
dnaX | tmk | HMPREF0179_05205 | HMPREF0179_02510 | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.484 |
dnaX | topA | HMPREF0179_05205 | HMPREF0179_03009 | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.596 |
recO | recR | HMPREF0179_01641 | HMPREF0179_02452 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | Recombination protein recR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.955 |
recO | topA | HMPREF0179_01641 | HMPREF0179_03009 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.592 |