Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFV42853.1Efflux pump membrane protein. (408 aa)    
Predicted Functional Partners:
EFV42854.1
drug:H+ antiporter-2 (14 Spanner) (DHA2) family drug resistance MFS transporter; Belongs to the major facilitator superfamily.
 
 0.978
EFV44800.1
drug:H+ antiporter-2 (14 Spanner) (DHA2) family drug resistance MFS transporter; Belongs to the major facilitator superfamily.
 
 
 0.882
macB
Macrolide transport system ATP-binding/permease; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
  
 0.798
EFV42855.1
Hypothetical protein.
     
 0.768
EFV44309.1
NodT family efflux transporter, outer membrane factor (OMF) lipoprotein.
 
 
 0.767
EFV42960.1
NodT family efflux transporter, outer membrane factor (OMF) lipoprotein.
 
 
 0.741
EFV46125.2
Hypothetical protein.
 
 
 0.740
EFV45393.1
NodT family efflux transporter, outer membrane factor (OMF) lipoprotein.
 
 
 0.736
EFV45426.1
NodT family efflux transporter, outer membrane factor (OMF) lipoprotein.
 
 
 0.726
EFV42687.2
Hypothetical protein.
 
 
 0.630
Your Current Organism:
Bilophila wadsworthia
NCBI taxonomy Id: 563192
Other names: B. wadsworthia 3_1_6, Bilophila wadsworthia 3_1_6, Bilophila wadsworthia str. 3_1_6, Bilophila wadsworthia strain 3_1_6
Server load: low (16%) [HD]