STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHK63870.1Succinate dehydrogenase subunit C. (125 aa)    
Predicted Functional Partners:
SHK63892.1
Succinate dehydrogenase / fumarate reductase membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
 
 0.999
SHK63910.1
Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.999
SHK63937.1
Succinate dehydrogenase subunit B.
 
 0.999
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.998
sucD
succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.996
SHK82089.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.993
SHK22432.1
Fumarase, class II.
   
 
 0.989
SHK65528.1
NAD-dependent formate dehydrogenase flavoprotein subunit.
   
  
 0.966
SHK18384.1
Succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
  0.965
SHK40421.1
Succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
  0.965
Your Current Organism:
Marinobacter antarcticus
NCBI taxonomy Id: 564117
Other names: CGMCC 1.10835, KCTC 23684, M. antarcticus, Marinobacter antarcticus Liu et al. 2012, Marinobacter sp. ZS2-30, strain ZS2-30
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