node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDW31404.1 | SDW31480.1 | SAMN04488238_101615 | SAMN04488238_101617 | Amino acid/amide ABC transporter substrate-binding protein, HAAT family (TC 3.A.1.4.-). | Putative endonuclease; Belongs to the UPF0102 family. | 0.738 |
SDW31404.1 | SDX33810.1 | SAMN04488238_101615 | SAMN04488238_107153 | Amino acid/amide ABC transporter substrate-binding protein, HAAT family (TC 3.A.1.4.-). | Glutamate synthase (NADPH/NADH) large chain. | 0.432 |
SDW31404.1 | glnD | SAMN04488238_101615 | SAMN04488238_101614 | Amino acid/amide ABC transporter substrate-binding protein, HAAT family (TC 3.A.1.4.-). | UTP--GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.855 |
SDW31404.1 | murJ | SAMN04488238_101615 | SAMN04488238_101613 | Amino acid/amide ABC transporter substrate-binding protein, HAAT family (TC 3.A.1.4.-). | Putative peptidoglycan lipid II flippase; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.855 |
SDW31404.1 | rsmI | SAMN04488238_101615 | SAMN04488238_101616 | Amino acid/amide ABC transporter substrate-binding protein, HAAT family (TC 3.A.1.4.-). | 16S rRNA (cytidine1402-2'-O)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.771 |
SDW31480.1 | SDW31404.1 | SAMN04488238_101617 | SAMN04488238_101615 | Putative endonuclease; Belongs to the UPF0102 family. | Amino acid/amide ABC transporter substrate-binding protein, HAAT family (TC 3.A.1.4.-). | 0.738 |
SDW31480.1 | glnD | SAMN04488238_101617 | SAMN04488238_101614 | Putative endonuclease; Belongs to the UPF0102 family. | UTP--GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.738 |
SDW31480.1 | murJ | SAMN04488238_101617 | SAMN04488238_101613 | Putative endonuclease; Belongs to the UPF0102 family. | Putative peptidoglycan lipid II flippase; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.738 |
SDW31480.1 | rsmI | SAMN04488238_101617 | SAMN04488238_101616 | Putative endonuclease; Belongs to the UPF0102 family. | 16S rRNA (cytidine1402-2'-O)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.872 |
SDW76921.1 | SDX33810.1 | SAMN04488238_103302 | SAMN04488238_107153 | Nitrogen regulatory protein P-II family; Belongs to the P(II) protein family. | Glutamate synthase (NADPH/NADH) large chain. | 0.820 |
SDW76921.1 | SDX49122.1 | SAMN04488238_103302 | SAMN04488238_10920 | Nitrogen regulatory protein P-II family; Belongs to the P(II) protein family. | Two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL. | 0.980 |
SDW76921.1 | SDX50200.1 | SAMN04488238_103302 | SAMN04488238_10960 | Nitrogen regulatory protein P-II family; Belongs to the P(II) protein family. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.431 |
SDW76921.1 | glnD | SAMN04488238_103302 | SAMN04488238_101614 | Nitrogen regulatory protein P-II family; Belongs to the P(II) protein family. | UTP--GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.950 |
SDX33810.1 | SDW31404.1 | SAMN04488238_107153 | SAMN04488238_101615 | Glutamate synthase (NADPH/NADH) large chain. | Amino acid/amide ABC transporter substrate-binding protein, HAAT family (TC 3.A.1.4.-). | 0.432 |
SDX33810.1 | SDW76921.1 | SAMN04488238_107153 | SAMN04488238_103302 | Glutamate synthase (NADPH/NADH) large chain. | Nitrogen regulatory protein P-II family; Belongs to the P(II) protein family. | 0.820 |
SDX33810.1 | SDX35499.1 | SAMN04488238_107153 | SAMN04488238_107208 | Glutamate synthase (NADPH/NADH) large chain. | Nitrogen regulatory protein P-II family; Belongs to the P(II) protein family. | 0.821 |
SDX33810.1 | SDX49122.1 | SAMN04488238_107153 | SAMN04488238_10920 | Glutamate synthase (NADPH/NADH) large chain. | Two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL. | 0.628 |
SDX33810.1 | SDX50200.1 | SAMN04488238_107153 | SAMN04488238_10960 | Glutamate synthase (NADPH/NADH) large chain. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.706 |
SDX33810.1 | glnD | SAMN04488238_107153 | SAMN04488238_101614 | Glutamate synthase (NADPH/NADH) large chain. | UTP--GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.805 |
SDX35499.1 | SDX33810.1 | SAMN04488238_107208 | SAMN04488238_107153 | Nitrogen regulatory protein P-II family; Belongs to the P(II) protein family. | Glutamate synthase (NADPH/NADH) large chain. | 0.821 |