node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDW06194.1 | SDW08563.1 | SAMN04488238_1011 | SAMN04488238_10156 | Integrase core domain-containing protein. | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.652 |
SDW06194.1 | SDW43035.1 | SAMN04488238_1011 | SAMN04488238_10251 | Integrase core domain-containing protein. | cob(II)yrinic acid a,c-diamide reductase. | 0.746 |
SDW06194.1 | SDX51092.1 | SAMN04488238_1011 | SAMN04488238_10987 | Integrase core domain-containing protein. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.510 |
SDW08563.1 | SDW06194.1 | SAMN04488238_10156 | SAMN04488238_1011 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Integrase core domain-containing protein. | 0.652 |
SDW08563.1 | SDW43035.1 | SAMN04488238_10156 | SAMN04488238_10251 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | cob(II)yrinic acid a,c-diamide reductase. | 0.829 |
SDW08563.1 | SDW53494.1 | SAMN04488238_10156 | SAMN04488238_102335 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.976 |
SDW08563.1 | SDW53807.1 | SAMN04488238_10156 | SAMN04488238_102342 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.966 |
SDW08563.1 | SDW53855.1 | SAMN04488238_10156 | SAMN04488238_102343 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | precorrin-8X methylmutase. | 0.660 |
SDW08563.1 | SDX51092.1 | SAMN04488238_10156 | SAMN04488238_10987 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.673 |
SDW08563.1 | cobT | SAMN04488238_10156 | SAMN04488238_10990 | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.717 |
SDW43035.1 | SDW06194.1 | SAMN04488238_10251 | SAMN04488238_1011 | cob(II)yrinic acid a,c-diamide reductase. | Integrase core domain-containing protein. | 0.746 |
SDW43035.1 | SDW08563.1 | SAMN04488238_10251 | SAMN04488238_10156 | cob(II)yrinic acid a,c-diamide reductase. | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.829 |
SDW43035.1 | SDW53494.1 | SAMN04488238_10251 | SAMN04488238_102335 | cob(II)yrinic acid a,c-diamide reductase. | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.944 |
SDW43035.1 | SDW53807.1 | SAMN04488238_10251 | SAMN04488238_102342 | cob(II)yrinic acid a,c-diamide reductase. | Precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.807 |
SDW43035.1 | SDW53855.1 | SAMN04488238_10251 | SAMN04488238_102343 | cob(II)yrinic acid a,c-diamide reductase. | precorrin-8X methylmutase. | 0.713 |
SDW43035.1 | SDW89158.1 | SAMN04488238_10251 | SAMN04488238_104106 | cob(II)yrinic acid a,c-diamide reductase. | Crotonobetainyl-CoA:carnitine CoA-transferase CaiB; Belongs to the CoA-transferase III family. | 0.679 |
SDW43035.1 | SDX13474.1 | SAMN04488238_10251 | SAMN04488238_105279 | cob(II)yrinic acid a,c-diamide reductase. | NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family. | 0.783 |
SDW43035.1 | SDX29661.1 | SAMN04488238_10251 | SAMN04488238_10717 | cob(II)yrinic acid a,c-diamide reductase. | NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family. | 0.783 |
SDW43035.1 | SDX51092.1 | SAMN04488238_10251 | SAMN04488238_10987 | cob(II)yrinic acid a,c-diamide reductase. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.947 |
SDW43035.1 | cobT | SAMN04488238_10251 | SAMN04488238_10990 | cob(II)yrinic acid a,c-diamide reductase. | Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.996 |