node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDW30513.1 | SDW56253.1 | SAMN04488238_101595 | SAMN04488238_102403 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | 4-hydroxyphenylpyruvate dioxygenase. | 0.605 |
SDW30513.1 | SDX10043.1 | SAMN04488238_101595 | SAMN04488238_105179 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | 0.782 |
SDW30513.1 | SDX20626.1 | SAMN04488238_101595 | SAMN04488238_10661 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase subunit beta. | 0.838 |
SDW30513.1 | SDX20678.1 | SAMN04488238_101595 | SAMN04488238_10663 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase subunit delta. | 0.999 |
SDW30513.1 | SDX20712.1 | SAMN04488238_101595 | SAMN04488238_10664 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase subunit alpha; Belongs to the GcvT family. | 0.997 |
SDW30513.1 | SDX20740.1 | SAMN04488238_101595 | SAMN04488238_10665 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase subunit gamma. | 0.999 |
SDW30513.1 | SDX33810.1 | SAMN04488238_101595 | SAMN04488238_107153 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Glutamate synthase (NADPH/NADH) large chain. | 0.961 |
SDW30513.1 | gcvP | SAMN04488238_101595 | SAMN04488238_106227 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.998 |
SDW30513.1 | glyA | SAMN04488238_101595 | SAMN04488238_102462 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.917 |
SDW56253.1 | SDW30513.1 | SAMN04488238_102403 | SAMN04488238_101595 | 4-hydroxyphenylpyruvate dioxygenase. | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | 0.605 |
SDW56253.1 | SDX20626.1 | SAMN04488238_102403 | SAMN04488238_10661 | 4-hydroxyphenylpyruvate dioxygenase. | Sarcosine oxidase subunit beta. | 0.678 |
SDX10043.1 | SDW30513.1 | SAMN04488238_105179 | SAMN04488238_101595 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | 0.782 |
SDX10043.1 | SDX20626.1 | SAMN04488238_105179 | SAMN04488238_10661 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | Sarcosine oxidase subunit beta. | 0.816 |
SDX10043.1 | SDX20678.1 | SAMN04488238_105179 | SAMN04488238_10663 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | Sarcosine oxidase subunit delta. | 0.884 |
SDX10043.1 | SDX20740.1 | SAMN04488238_105179 | SAMN04488238_10665 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | Sarcosine oxidase subunit gamma. | 0.811 |
SDX10043.1 | SDX33810.1 | SAMN04488238_105179 | SAMN04488238_107153 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | Glutamate synthase (NADPH/NADH) large chain. | 0.900 |
SDX10043.1 | gcvP | SAMN04488238_105179 | SAMN04488238_106227 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.706 |
SDX10043.1 | glyA | SAMN04488238_105179 | SAMN04488238_102462 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.518 |
SDX20626.1 | SDW30513.1 | SAMN04488238_10661 | SAMN04488238_101595 | Sarcosine oxidase subunit beta. | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | 0.838 |
SDX20626.1 | SDW56253.1 | SAMN04488238_10661 | SAMN04488238_102403 | Sarcosine oxidase subunit beta. | 4-hydroxyphenylpyruvate dioxygenase. | 0.678 |