SDX59840.1 protein (Roseicitreum antarcticum)

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experimentally determined

Predicted Interactions

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Score

SDX59840.1

3-oxoacyl-[acyl-carrier protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (240 aa)

Predicted Functional Partners:

SDX59872.1

0.856

SDX59808.1

0.823

SDX90059.1

0.782

SDW10514.1

0.775

SDX10318.1

0.765

SDW24382.1

0.739

SDW55245.1

0.739

SDX59775.1

0.729

SDX59738.1

0.727

SDX59902.1

0.663

Your Current Organism:

Roseicitreum antarcticum

NCBI taxonomy Id: 564137
Other names: CGMCC 1.8894, LMG 24863, LMG:24863, R. antarcticum, Rhodobacter sp. ZS2-28, Roseicitreum antarcticum Yu et al. 2011, strain ZS2-28

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDW10514.1	SDW24382.1	SAMN04488238_101103	SAMN04488238_101451	7-alpha-hydroxysteroid dehydrogenase.	Acyl transferase domain-containing protein.	0.906
SDW10514.1	SDX59840.1	SAMN04488238_101103	SAMN04488238_11140	7-alpha-hydroxysteroid dehydrogenase.	3-oxoacyl-[acyl-carrier protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.775
SDW24382.1	SDW10514.1	SAMN04488238_101451	SAMN04488238_101103	Acyl transferase domain-containing protein.	7-alpha-hydroxysteroid dehydrogenase.	0.906
SDW24382.1	SDW55245.1	SAMN04488238_101451	SAMN04488238_102377	Acyl transferase domain-containing protein.	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family.	0.906
SDW24382.1	SDX10318.1	SAMN04488238_101451	SAMN04488238_105187	Acyl transferase domain-containing protein.	3-oxoacyl-[acyl-carrier protein] reductase.	0.906
SDW24382.1	SDX59840.1	SAMN04488238_101451	SAMN04488238_11140	Acyl transferase domain-containing protein.	3-oxoacyl-[acyl-carrier protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.739
SDW24382.1	SDX90059.1	SAMN04488238_101451	SAMN04488238_1393	Acyl transferase domain-containing protein.	2-hydroxycyclohexanecarboxyl-CoA dehydrogenase.	0.906
SDW55245.1	SDW24382.1	SAMN04488238_102377	SAMN04488238_101451	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family.	Acyl transferase domain-containing protein.	0.906
SDW55245.1	SDX59840.1	SAMN04488238_102377	SAMN04488238_11140	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family.	3-oxoacyl-[acyl-carrier protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.739
SDX10318.1	SDW24382.1	SAMN04488238_105187	SAMN04488238_101451	3-oxoacyl-[acyl-carrier protein] reductase.	Acyl transferase domain-containing protein.	0.906
SDX10318.1	SDX59840.1	SAMN04488238_105187	SAMN04488238_11140	3-oxoacyl-[acyl-carrier protein] reductase.	3-oxoacyl-[acyl-carrier protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.765
SDX59738.1	SDX59775.1	SAMN04488238_11137	SAMN04488238_11138	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family.	Zinc carboxypeptidase.	0.773
SDX59738.1	SDX59808.1	SAMN04488238_11137	SAMN04488238_11139	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family.	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase.	0.727
SDX59738.1	SDX59840.1	SAMN04488238_11137	SAMN04488238_11140	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family.	3-oxoacyl-[acyl-carrier protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.727
SDX59738.1	SDX59872.1	SAMN04488238_11137	SAMN04488238_11141	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family.	Predicted dehydrogenase.	0.727
SDX59738.1	SDX59902.1	SAMN04488238_11137	SAMN04488238_11142	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family.	Peptide/nickel transport system substrate-binding protein.	0.545
SDX59775.1	SDX59738.1	SAMN04488238_11138	SAMN04488238_11137	Zinc carboxypeptidase.	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family.	0.773
SDX59775.1	SDX59808.1	SAMN04488238_11138	SAMN04488238_11139	Zinc carboxypeptidase.	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase.	0.727
SDX59775.1	SDX59840.1	SAMN04488238_11138	SAMN04488238_11140	Zinc carboxypeptidase.	3-oxoacyl-[acyl-carrier protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.729
SDX59775.1	SDX59872.1	SAMN04488238_11138	SAMN04488238_11141	Zinc carboxypeptidase.	Predicted dehydrogenase.	0.754

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

23

average node degree:

4.18

avg. local clustering coefficient:

0.896

expected number of edges:

10

PPI enrichment p-value:

0.000465

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006418

tRNA aminoacylation for protein translation

10 of 23

2.15

6.76

1.43e-17

GO:0006520

Cellular amino acid metabolic process

11 of 151

1.37

2.55

3.12e-13

GO:0044271

Cellular nitrogen compound biosynthetic process

11 of 337

1.02

1.34

4.97e-10

GO:1901566

Organonitrogen compound biosynthetic process

11 of 394

0.96

1.17

2.29e-09

GO:0006139

Nucleobase-containing compound metabolic process

11 of 479

0.87

0.98

1.74e-08

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004812

aminoacyl-tRNA ligase activity

10 of 23

2.15

6.83

7.78e-18

GO:0016874

Ligase activity

11 of 89

1.6

3.75

1.12e-15

GO:0002161

aminoacyl-tRNA editing activity

3 of 7

2.14

2.08

8.04e-05

GO:0000049

tRNA binding

4 of 28

1.67

1.83

5.45e-05

GO:0005524

ATP binding

11 of 311

1.06

1.43

3.21e-10

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 1203

0.47

0.39

0.00095

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:348

Aminoacyl-tRNA synthetase

5 of 15

2.03

2.81

1.17e-06

CL:350

Aminoacyl-tRNA synthetase

3 of 10

1.99

1.53

0.00094

CL:110

Translation, and Protein export

6 of 137

1.15

1.03

0.00059

CL:355

tRNA synthetases class I (M), and arginyl-tRNA aminoacylation

2 of 5

2.11

0.93

0.0182

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00970

Aminoacyl-tRNA biosynthesis

10 of 31

2.02

6.14

1.69e-17

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005737

Cytoplasm

11 of 1008

0.55

0.46

0.00029

GOCC:0005829

Cytosol

8 of 622

0.62

0.44

0.0089

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0030

Aminoacyl-tRNA synthetase

10 of 22

2.17

7.11

1.71e-18

KW-0648

Protein biosynthesis

10 of 49

1.82

4.85

5.53e-16

KW-0436

Ligase

11 of 69

1.71

4.49

3.92e-17

KW-0067

ATP-binding

11 of 252

1.15

1.72

1.58e-11

KW-0820

tRNA-binding

3 of 19

1.71

1.39

0.0011

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13603

Leucyl-tRNA synthetase, Domain 2

3 of 3

2.51

1.94

0.00025

PF08264

Anticodon-binding domain of tRNA ligase

3 of 3

2.51

1.94

0.00025

PF09334

tRNA synthetases class I (M)

3 of 4

2.39

1.92

0.00025

PF00587

tRNA synthetase class II core domain (G, H, P, S and T)

2 of 3

2.33

1.04

0.0122

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00863

Threonyl and Alanyl tRNA synthetase second additional domain

2 of 2

2.51

1.18

0.0070

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