AJC45591.1 protein (Xanthomonas sacchari) - STRING interaction network

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AJC45591.1

Guanosine polyphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)

Predicted Functional Partners:

rplK

0.696

rpsE

0.695

rpmE2

0.695

rpsL

0.694

rpsI

0.688

rplB

0.686

rplM

0.686

rpmJ

0.682

rplF

0.679

rpsO

0.678

Your Current Organism:

Xanthomonas sacchari

NCBI taxonomy Id: 56458
Other names: CFBP 4641, ICMP 16916, LMG 471, LMG:471, X. sacchari

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJC45591.1	rplB	SB85_07195	SB85_08195	Guanosine polyphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.686
AJC45591.1	rplF	SB85_07195	SB85_08135	Guanosine polyphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.	0.679
AJC45591.1	rplK	SB85_07195	SB85_08265	Guanosine polyphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.696
AJC45591.1	rplM	SB85_07195	SB85_11130	Guanosine polyphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.686
AJC45591.1	rpmE2	SB85_07195	SB85_17680	Guanosine polyphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L31 type B; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.695
AJC45591.1	rpmJ	SB85_07195	SB85_02910	Guanosine polyphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L36; Smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.682
AJC45591.1	rpsE	SB85_07195	SB85_08125	Guanosine polyphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	0.695
AJC45591.1	rpsI	SB85_07195	SB85_11125	Guanosine polyphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family.	0.688
AJC45591.1	rpsL	SB85_07195	SB85_08235	Guanosine polyphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.	0.694
AJC45591.1	rpsO	SB85_07195	SB85_05585	Guanosine polyphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.	0.678
rplB	AJC45591.1	SB85_08195	SB85_07195	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Guanosine polyphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.686
rplB	rplF	SB85_08195	SB85_08135	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.	0.999
rplB	rplK	SB85_08195	SB85_08265	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.998
rplB	rplM	SB85_08195	SB85_11130	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.998
rplB	rpmE2	SB85_08195	SB85_17680	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L31 type B; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.979
rplB	rpmJ	SB85_08195	SB85_02910	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L36; Smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
rplB	rpsE	SB85_08195	SB85_08125	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	0.999
rplB	rpsI	SB85_08195	SB85_11125	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family.	0.998
rplB	rpsL	SB85_08195	SB85_08235	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.	0.998
rplB	rpsO	SB85_08195	SB85_05585	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.	0.997