prpF protein (Xanthomonas sacchari) - STRING interaction network

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[Homology]

Score

prpF

3-methylitaconate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)

Predicted Functional Partners:

acnD

0.991

acnA

0.970

acnB

0.923

prpB

0.874

AJC45629.1

0.722

AJC45632.1

0.437

gltA

0.437

glpK

0.428

Your Current Organism:

Xanthomonas sacchari

NCBI taxonomy Id: 56458
Other names: CFBP 4641, ICMP 16916, LMG 471, LMG:471, X. sacchari

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJC45629.1	AJC45632.1	SB85_07410	SB85_07425	Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology.	Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.953
AJC45629.1	acnA	SB85_07410	SB85_01490	Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.	0.980
AJC45629.1	acnB	SB85_07410	SB85_01505	Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology.	Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family.	0.948
AJC45629.1	acnD	SB85_07410	SB85_07405	Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aconitate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.992
AJC45629.1	glpK	SB85_07410	SB85_15510	Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.	0.424
AJC45629.1	gltA	SB85_07410	SB85_17685	Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology.	Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.	0.917
AJC45629.1	prpB	SB85_07410	SB85_07420	Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.	0.978
AJC45629.1	prpF	SB85_07410	SB85_07400	Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-methylitaconate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.722
AJC45632.1	AJC45629.1	SB85_07425	SB85_07410	Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.953
AJC45632.1	acnA	SB85_07425	SB85_01490	Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.	0.983
AJC45632.1	acnB	SB85_07425	SB85_01505	Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family.	0.948
AJC45632.1	acnD	SB85_07425	SB85_07405	Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aconitate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.876
AJC45632.1	glpK	SB85_07425	SB85_15510	Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.	0.424
AJC45632.1	gltA	SB85_07425	SB85_17685	Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.	0.926
AJC45632.1	prpB	SB85_07425	SB85_07420	Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.	0.872
AJC45632.1	prpF	SB85_07425	SB85_07400	Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-methylitaconate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.437
acnA	AJC45629.1	SB85_01490	SB85_07410	Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.	Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.980
acnA	AJC45632.1	SB85_01490	SB85_07425	Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.	Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.983
acnA	acnB	SB85_01490	SB85_01505	Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.	Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family.	0.957
acnA	gltA	SB85_01490	SB85_17685	Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.	Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.	0.979