Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ahcYS-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (481 aa)    
Predicted Functional Partners:
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.968
AJC46015.1
Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.941
AJC47475.1
5-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.934
AJC44949.1
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.933
metB
Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.919
AJC44421.1
O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.913
AJC46173.1
DNA (cytosine-5-)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.904
AJC45399.1
Homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
AJC46014.1
Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.838
AJC46032.1
Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.836
Your Current Organism:
Xanthomonas sacchari
NCBI taxonomy Id: 56458
Other names: CFBP 4641, ICMP 16916, LMG 471, LMG:471, X. sacchari
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