| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJC46314.1 | AJC46315.1 | SB85_11620 | SB85_11625 | Flavodoxin; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.898 |
| AJC46314.1 | AJC47616.1 | SB85_11620 | SB85_11630 | Flavodoxin; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.827 |
| AJC46315.1 | AJC46314.1 | SB85_11625 | SB85_11620 | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Flavodoxin; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.898 |
| AJC46315.1 | AJC46918.1 | SB85_11625 | SB85_15420 | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
| AJC46315.1 | AJC46920.1 | SB85_11625 | SB85_15430 | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | NrdJb; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.922 |
| AJC46315.1 | AJC47305.1 | SB85_11625 | SB85_17660 | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | (p)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.902 |
| AJC46315.1 | AJC47616.1 | SB85_11625 | SB85_11630 | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.999 |
| AJC46315.1 | adk | SB85_11625 | SB85_17425 | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.927 |
| AJC46315.1 | gmk | SB85_11625 | SB85_17650 | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.908 |
| AJC46315.1 | ndk | SB85_11625 | SB85_02850 | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.913 |
| AJC46315.1 | thyA | SB85_11625 | SB85_08730 | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.603 |
| AJC46315.1 | tmk | SB85_11625 | SB85_07495 | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.949 |
| AJC46918.1 | AJC46315.1 | SB85_15420 | SB85_11625 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.997 |
| AJC46918.1 | AJC46920.1 | SB85_15420 | SB85_15430 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NrdJb; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.985 |
| AJC46918.1 | AJC47305.1 | SB85_15420 | SB85_17660 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | (p)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.901 |
| AJC46918.1 | AJC47616.1 | SB85_15420 | SB85_11630 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.910 |
| AJC46918.1 | adk | SB85_15420 | SB85_17425 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.926 |
| AJC46918.1 | gmk | SB85_15420 | SB85_17650 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.905 |
| AJC46918.1 | ndk | SB85_15420 | SB85_02850 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.908 |
| AJC46918.1 | thyA | SB85_15420 | SB85_08730 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.707 |