STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
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[Homology]
Score
AJC46645.1uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)    
Predicted Functional Partners:
AJC46646.1
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 
 0.980
AJC46644.1
Porphyrin biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.957
AJC47077.1
Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.905
cobA
uroporphyrin-III methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
     
 0.905
AJC46227.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.751
AJC47596.1
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.746
AJC44905.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.740
AJC47225.1
RstR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.736
AJC47566.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.701
AJC44901.1
Signal peptide protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.693
Your Current Organism:
Xanthomonas sacchari
NCBI taxonomy Id: 56458
Other names: CFBP 4641, ICMP 16916, LMG 471, LMG:471, X. sacchari
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