| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJC46315.1 | AJC46918.1 | SB85_11625 | SB85_15420 | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
| AJC46315.1 | AJC46920.1 | SB85_11625 | SB85_15430 | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | NrdJb; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.922 |
| AJC46315.1 | AJC47549.1 | SB85_11625 | SB85_08035 | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.467 |
| AJC46315.1 | AJC47616.1 | SB85_11625 | SB85_11630 | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.999 |
| AJC46315.1 | thyA | SB85_11625 | SB85_08730 | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.603 |
| AJC46480.1 | AJC46918.1 | SB85_12625 | SB85_15420 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.742 |
| AJC46480.1 | AJC46920.1 | SB85_12625 | SB85_15430 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | NrdJb; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.577 |
| AJC46480.1 | AJC47616.1 | SB85_12625 | SB85_11630 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.577 |
| AJC46480.1 | polA | SB85_12625 | SB85_12225 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.989 |
| AJC46480.1 | thyA | SB85_12625 | SB85_08730 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.792 |
| AJC46918.1 | AJC46315.1 | SB85_15420 | SB85_11625 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.997 |
| AJC46918.1 | AJC46480.1 | SB85_15420 | SB85_12625 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.742 |
| AJC46918.1 | AJC46919.1 | SB85_15420 | SB85_15425 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Major vault protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.448 |
| AJC46918.1 | AJC46920.1 | SB85_15420 | SB85_15430 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NrdJb; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.985 |
| AJC46918.1 | AJC47287.1 | SB85_15420 | SB85_17540 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.487 |
| AJC46918.1 | AJC47433.1 | SB85_15420 | SB85_00915 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.658 |
| AJC46918.1 | AJC47549.1 | SB85_15420 | SB85_08035 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.675 |
| AJC46918.1 | AJC47616.1 | SB85_15420 | SB85_11630 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.910 |
| AJC46918.1 | polA | SB85_15420 | SB85_12225 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.799 |
| AJC46918.1 | thyA | SB85_15420 | SB85_08730 | Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.707 |
