STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2F3W4General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (483 aa)    
Predicted Functional Partners:
A0A1Y2F2W2
DNA repair helicase RAD3.
    
 0.999
A0A1Y2F5X7
Transcription factor TFIIH complex ERCC-3 subunit.
    
 0.999
A0A1Y2F8S0
RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
   
 0.999
A0A1Y2FNS5
TFIIH subunit Tfb4/p34.
   
 0.999
A0A1Y2FUG9
Uncharacterized protein.
    
 0.999
A0A1Y2FIL7
TFIIH subunit TTDA/Tfb5.
    
 0.997
A0A1Y2FDU8
CDK-activating kinase assembly factor MAT1-domain-containing protein.
   
 0.994
A0A1Y2FBU8
TFA2 protein.
   
 0.986
A0A1Y2FP57
TFIIE alpha subunit-domain-containing protein.
   
 0.986
A0A1Y2FLS6
Kinase-like domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.983
Your Current Organism:
Protomyces lactucaedebilis
NCBI taxonomy Id: 56484
Other names: NRRL YB-4353, P. lactucaedebilis
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