STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2FCM0Indigoidine synthase A like protein-domain-containing protein. (727 aa)    
Predicted Functional Partners:
A0A1Y2FS32
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
  0.852
A0A1Y2F8U4
WD40-repeat-containing domain protein.
 
      0.819
A0A1Y2FC15
Inosine/uridine-preferring nucleoside hydrolase domain-containing protein.
  
 
  0.753
A0A1Y2FKM5
Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
   
 
  0.752
A0A1Y2EYL6
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 
 0.716
A0A1Y2EV54
Ribokinase-like protein.
  
 
 0.713
A0A1Y2F832
PfkB family carbohydrate kinase.
  
 
 0.713
A0A1Y2FQM2
Dihydrofolate reductase-like domain-containing protein.
  
 
 0.713
A0A1Y2FUJ5
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
  0.617
A0A1Y2FRC1
Uracil-5--methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
     
 0.564
Your Current Organism:
Protomyces lactucaedebilis
NCBI taxonomy Id: 56484
Other names: NRRL YB-4353, P. lactucaedebilis
Server load: low (26%) [HD]