STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2FH28Uncharacterized protein. (1895 aa)    
Predicted Functional Partners:
A0A1Y2FK30
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.964
A0A1Y2FDR0
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 0.959
A0A1Y2F0I3
Uncharacterized protein.
   
 0.949
A0A1Y2EU87
DUF1767 domain-containing protein.
    
 0.943
A0A1Y2F582
Mating-type switching protein swi10.
    
 0.927
A0A1Y2EYF4
3'-5' exonuclease domain-containing protein.
   
 0.912
A0A1Y2EYK6
Ribonuclease H-like domain-containing protein.
   
 0.912
A0A1Y2FI93
Putative DNA repair protein Mus81.
    
 0.905
A0A1Y2F4A2
Ribosomal protein; Belongs to the universal ribosomal protein uL1 family.
    
 0.903
A0A1Y2FED9
NPL4 family-domain-containing protein.
    
 0.898
Your Current Organism:
Protomyces lactucaedebilis
NCBI taxonomy Id: 56484
Other names: NRRL YB-4353, P. lactucaedebilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.